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Calcium Green 1 potassium salt
| Catalog Number | A14-0032 |
| Category | Calcium, Chloride and Other indicators |
| Molecular Formula | C43H27Cl2K6N3O16 |
| Molecular Weight | 1147.2 |
| Catalog Number | Size | Price | Quantity |
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Product Introduction
Calcium Green 1 is a cell-impermeant fluorescent calcium indicator that is suitable for detecting low levels of calcium such as in resting cells.
Chemical Information |
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| Synonyms | 2,2'-((2-(2-(2-(bis(carboxylatomethyl)amino)-5-(3-carboxylato-4-(2,7-dichloro-6-oxido-3-oxo-3H-xanthen-9-yl)benzamido)phenoxy)ethoxy)phenyl)azanediyl)diacetate, hexapotassium salt |
| Purity | ≥90% |
| Canonical SMILES | C1=CC=C(C(=C1)N(CC(=O)[O-])CC(=O)[O-])OCCOC2=C(C=CC(=C2)NC(=O)C3=CC(=C(C=C3)C4=C5C=C(C(=O)C=C5OC6=CC(=C(C=C64)Cl)[O-])Cl)C(=O)[O-])N(CC(=O)[O-])CC(=O)[O-].[K+].[K+].[K+].[K+].[K+].[K+] |
| InChI | InChI=1S/C43H33Cl2N3O16.6K/c44-27-13-25-34(15-31(27)49)64-35-16-32(50)28(45)14-26(35)41(25)23-7-5-21(11-24(23)43(60)61)42(59)46-22-6-8-30(48(19-39(55)56)20-40(57)58)36(12-22)63-10-9-62-33-4-2-1-3-29(33)47(17-37(51)52)18-38(53)54;;;;;;/h1-8,11-16,49H,9-10,17-20H2,(H,46,59)(H,51,52)(H,53,54)(H,55,56)(H,57,58)(H,60,61);;;;;;/q;6*+1/p-6 |
| InChI Key | BLDOQCXFPCZYKG-UHFFFAOYSA-H |
| Appearance | Solid Powder |
- Product Specification
- Application
| Excitation | 506 nm |
| Emission | 531 nm |
| Storage | Store at -20°C |
Calcium Green 1 potassium salt, a fluorescent dye renowned for measuring intracellular calcium concentrations, finds wide-ranging applications in biological research.
Cell Imaging: Embraced in fluorescence microscopy, Calcium Green 1 potassium salt serves as a beacon for visualizing and tracking calcium signaling dynamics within live cells. By injecting the dye into cells, researchers embark on a journey to unveil real-time calcium fluctuations, unlocking insights into cellular responses to diverse stimuli. This technique sheds light on calcium-dependent processes like muscle contraction, neurotransmission, and cell proliferation.
Neuroscience: In the labyrinth of neuroscience inquiry, Calcium Green 1 potassium salt emerges as a pivotal tool for unraveling neuronal activity and calcium dynamics within brain tissue. Researchers harness this dye to witness the ebb and flow of calcium in neurons during synaptic transmission and neuronal firing, peering into the intricate mechanisms underpinning learning, memory, and neurodegenerative disorders.
Cardiac Research: Delving into the domain of cardiomyocyte studies, Calcium Green 1 potassium salt takes center stage in deciphering calcium transients dictating heart muscle contractions. By visualizing the rhythmic dance of calcium waves and scrutinizing their patterns, scientists unravel the tapestry of cardiac physiology and pathology. This application plays a pivotal role in exploring heart conditions, assessing drug impacts on cardiac functionality, and forging novel therapeutic pathways.
Drug Screening: In the pharmaceutical arena, Calcium Green 1 potassium salt emerges as a beacon for high-throughput screening assays to pinpoint compounds modulating intracellular calcium levels. By correlating variations in fluorescence intensity with calcium concentrations, researchers rapidly assess the impacts of myriad drug candidates, expediting the discovery and development of potential therapeutics targeting calcium signaling pathways.
Applications of Fluorescent Probes & Dyes
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