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9-Amino-6-chloro-2-methoxyacridine

Catelog Number: A19-0004

Category: DNA Stains

Description

9-Amino-6-chloro-2-methoxyacridine (ACMA) is a cell-permeable fluorescent probe for labeling DNA with selectivity for poly(dA-dT) sequences. ACMA fluorescence is quenched when a pH gradient is established, a property that has been utilized in animal-and plant-based studies. It also inhibits acetylcholinesterase with a Ki value of 49 nM.

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Chemical Information
Catelog Number: A19-0004
Product Name: 9-Amino-6-chloro-2-methoxyacridine
CAS Number: 3548-09-2
Molecular Formula: C14H11ClN2O
Molecular Weight: 258.7
Purity: ≥98%
Synonyms: ACMA; 6-chloro-2-methoxy-9-acridinamine
Product Specification
Appearance: Solid Powder
Excitation Maximum: 411
Storage Conditions: Store at -20°C
Additional Information
InChI: InChI=1S/C14H11ClN2O/c1-18-9-3-5-12-11(7-9)14(16)10-4-2-8(15)6-13(10)17-12/h2-7H,1H3,(H2,16,17)
InChIKey: IHHSSHCBRVYGJX-UHFFFAOYSA-N
CanonicalSMILES: COC1=CC2=C(C3=C(C=C(C=C3)Cl)N=C2C=C1)N

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