7-Amino-4-chloromethylcoumarin | 147963-22-2

Catelog Number	A16-0077
Category	Cell proliferation tracer Fluorescent Probes
Molecular Formula	C10H8NO2Cl
Molecular Weight	209.63

Catalog Number	Size	Price	Quantity
A16-0077	--	$--

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Product Introduction

7-Amino-4-chloromethylcoumarin is a thiol-reactive, cell-permeant, fluorescent probe that is commonly used as a long-term cell tracer. It is well retained in cells for at least 24 hours.

Chemical Information
Synonyms	CellHunt Blue CMAC; 7-amino-4-(chloromethyl)-2H-chromen-2-one; 7-amino-4-(chloromethyl)chromen-2-one
IUPAC Name	7-amino-4-(chloromethyl)chromen-2-one
Canonical SMILES	C1=CC2=C(C=C1N)OC(=O)C=C2CCl
InChI	InChI=1S/C10H8ClNO2/c11-5-6-3-10(13)14-9-4-7(12)1-2-8(6)9/h1-4H,5,12H2
InChI Key	VIEYMVWPECAOCY-UHFFFAOYSA-N

Computed Properties
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	1
Exact Mass	209.0243562 g/mol
Monoisotopic Mass	209.0243562 g/mol
Topological Polar Surface Area	52.3Å²
Heavy Atom Count	14
Formal Charge	0
Complexity	277
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Literatures

PMID	Publication Date	Title	Journal
20162389	2011-01-01	Wallerian-like degeneration of central neurons after synchronized and geometrically registered mass axotomy in a three-compartmental microfluidic chip	Neurotoxicity research
21765948	2011-01-01	Calpain and PARP activation during photoreceptor cell death in P23H and S334ter rhodopsin mutant rats	PloS one
21184674	2010-12-24	Tetherin restricts direct cell-to-cell infection of HIV-1	Retrovirology
21049044	2010-10-25	Moderation of calpain activity promotes neovascular integration and lumen formation during VEGF-induced pathological angiogenesis	PloS one
19114102	2009-04-01	Spitzenkörper, vacuoles, ring-like structures, and mitochondria of Phanerochaete velutina hyphal tips visualized with carboxy-DFFDA, CMAC and DiOC6(3)	Mycological research

Patents

Publication Number	Title	Priority Date
WO-2022240655-A1	Methods of using shaped particles in flow cytometers for assays on b cells and t cells	2021-05-10
EP-4071148-A1	Dichalcogenide prodrugs	2021-04-07
WO-2022214598-A1	Dichalcogenide prodrugs	2021-04-07
EP-4062942-A1	Disulfide-based prodrug compounds	2021-03-22
WO-2022200347-A1	Disulfide-based prodrug compounds	2021-03-22

Applications of Fluorescent Probes & Dyes

Laser Dye

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7-Amino-4-chloromethylcoumarin | 147963-22-2

Product Introduction

Chemical Information

Computed Properties

Literatures

Patents