Live Imaging of the Extracellular Matrix With a Glycan-Binding Fluorophore

June 9th, 2026 10:00 AM EDT

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3,3'-Diheptylthiacarbocyanine iodide

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3,3'-Diheptylthiacarbocyanine iodide

3,3'-Diheptylthiacarbocyanine iodide | CAS 53213-88-0

Catalog Number	A16-0166
Category	Cell membrane Fluorescent Probes
Molecular Formula	C31H41IN2S2
Molecular Weight	632.71

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Product Introduction

3,3'-Diheptylthiacarbocyanine iodide is a member of the cyanine dye family, characterized by its extended conjugated system that facilitates strong absorption and emission in the near-infrared region. This compound contains a thiacarbocyanine chromophore, which is known for its ability to participate in fluorescence resonance energy transfer (FRET) applications due to its spectral properties. It is commonly used as a membrane probe in fluorescence microscopy, where its lipophilic heptyl chains aid in anchoring the dye within lipid bilayers, enabling the study of membrane dynamics and organization.

Chemical Information
Product Specification
Application

Chemical Information

Synonyms	DiSC7(3)
SMILES	CCCCCCCN1C2=CC=CC=C2SC1=CC=CC3=[N+](C4=CC=CC=C4S3)CCCCCCC.[I-]
InChI	InChI=1S/C31H41N2S2.HI/c1-3-5-7-9-15-24-32-26-18-11-13-20-28(26)34-30(32)22-17-23-31-33(25-16-10-8-6-4-2)27-19-12-14-21-29(27)35-31;/h11-14,17-23H,3-10,15-16,24-25H2,1-2H3;1H/q+1;/p-1
InChIKey	QJIIDBGAPSEKOV-UHFFFAOYSA-M

Product Specification

Excitation	433
Emission	500

Application

3,3’-Diheptylthiacarbocyanine iodide, a fluorescent dye with diverse applications in biological and chemical research, offers a myriad of possibilities. Here are four key applications:

Cell Membrane Studies: Widely utilized for staining cell membranes, 3,3’-Diheptylthiacarbocyanine iodide’s strong affinity for lipid bilayers enables researchers to delve into the intricate dynamics of membranes. This staining technique allows for the visualization and scrutiny of membrane processes encompassing fusion, fission, and endocytosis. Particularly valuable in fluorescence microscopy, this dye facilitates the tracking of multifaceted cellular mechanisms.

Mitochondrial Function Analysis: In the realm of mitochondrial research, this dye proves invaluable for scrutinizing mitochondrial membrane potential. By accumulating in active mitochondria, researchers can gauge mitochondrial vitality and operation. Fluctuations in fluorescence intensity serve as indicators of various mitochondrial conditions, aiding in the exploration of metabolic maladies and apoptosis pathways.

Chemical Sensing: Beyond biological realms, 3,3’-Diheptylthiacarbocyanine iodide finds purpose in the domain of chemical sensors. Its fluorescence properties undergo transformations in response to diverse chemical environments, rendering it apt for detecting ions, pH alterations, and molecular interactions. This capability holds significance in environmental surveillance and diagnostic applications, fueling advancements in monitoring and testing methodologies.

Fluorescence Imaging: Emanating vibrant fluorescence, this dye stands out as a premier choice for high-resolution imaging endeavors. Its prowess in labeling and monitoring biological molecules within intricate systems, spanning tissues to live organisms, is unparalleled. This functionality plays a pivotal role in medical research and diagnostics, specifically in illuminating disease progression and evaluating treatment efficacy, marking a significant step forward in understanding biological intricacies.