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True BLUE chloride | CAS 71431-30-6
| Catalog Number | A16-0176 |
| Category | Other Cell Fluorescent Probes |
| Molecular Formula | C20H18Cl2N4O2 |
| Molecular Weight | 417.29 |
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
True BLUE chloride is a water-soluble, UV light-excitable, divalent cationic dye that stains the cytoplasm with blue fluorescence.
Chemical Information
Application
Computed Properties
Patents
| Synonyms | True blue; 5-Benzofurancarboximidamide, 2,2'-(1E)-1,2-ethenylbis-, dihydrochloride; (E)-2,2'-Vinylenedi-1-benzo(b)furane-5-carboxamidine dihydrochloride 2,2'-(1E)-1,2-ethenediylbis-5-benzofurancarboximidamide, dihydrochloride; 2,2'-(1,2-ethenediyl)bis-dihydrochloride dihydrochloride; 5-Benzofurancarboximidamide,2,2'-(1E)-1,2-ethenediylbis-,hydrochloride(1:2); 2-[(E)-2-(5-carbamimidoyl-1-benzofuran-2-yl)ethenyl]-1-benzofuran-5-carboximidamide;dihydrochloride |
| IUPAC Name | 2-[(E)-2-(5-carbamimidoyl-1-benzofuran-2-yl)ethenyl]-1-benzofuran-5-carboximidamide;dihydrochloride |
| Canonical SMILES | C1=CC2=C(C=C1C(=N)N)C=C(O2)/C=C/C3=CC4=C(O3)C=CC(=C4)C(=N)N.Cl.Cl |
| InChI | WFZFMHDDZRBTFH-CZEFNJPISA-N |
| InChIKey | C1=CC2=C(C=C1C(=N)N)C=C(O2)C=CC3=CC4=C(O3)C=CC(=C4)C(=N)N.Cl.Cl |
| Appearance | Solid Powder |
True BLUE chloride, a highly sensitive stain utilized in diverse biological and biotechnological contexts to visualize or quantify specific biological entities, showcases significant versatility. Here are four key applications of True BLUE chloride:
Histology: Within the realm of histology, True BLUE chloride serves as a cornerstone in staining techniques, offering unparalleled sensitivity for visualizing distinct cellular structures and tissues when examined under a microscope. Its refined specificity makes it an indispensable tool for conducting intricate tissue analyses. This application finds utility in both clinical diagnostics and research scenarios, facilitating a comprehensive comprehension of tissue architecture and pathology.
Neuroscience: In the expansive field of neuroscience, True BLUE chloride finds its purpose in tracing neuronal pathways and intricate connections within the brain and spinal cord. This stain is instrumental in aiding researchers to chart the complex networks of neurons, unraveling the mysteries of neural circuits. Such a technique plays a pivotal role in studying brain functionality, neurodevelopment, and the mechanisms underlying neurodegenerative disorders.
Immunohistochemistry: True BLUE chloride emerges as a vital component in immunohistochemical procedures, acting as an essential substrate to detect specific antigens within tissue sections. Its functionality as a chromogenic agent in enzyme-linked assays produces a distinct blue signal upon interaction with target antigens, facilitating the visualization of protein expression patterns and their spatial distribution in various tissues and cells.
Microbiology: Within microbiological studies, True BLUE chloride can be effectively harnessed to stain bacterial colonies and biofilms, enhancing the visual contrast of microbial samples. This heightened contrast aids researchers in better observing and quantifying microbial growth, morphology, and interactions, shedding light on crucial aspects of microbial ecology, pathogenesis, and the efficacy of antimicrobial interventions.
| Hydrogen Bond Donor Count | 6 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 4 |
| Exact Mass | 416.0806812 g/mol |
| Monoisotopic Mass | 416.0806812 g/mol |
| Topological Polar Surface Area | 126Ų |
| Heavy Atom Count | 28 |
| Formal Charge | 0 |
| Complexity | 542 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 1 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 3 |
| Compound Is Canonicalized | Yes |
| Publication Number | Title | Priority Date |
|---|---|---|
| CA-2686238-A1 | Metabotropic glutamate receptor 7(mglur7)-binding antibody | 2007-05-15 |
| CA-2686238-C | Metabotropic glutamate receptor 7(mglur7)-binding antibody | 2007-05-15 |
| JP-2010527921-A | Antibody to G protein coupled receptor (GPCR) | 2007-05-15 |
| JP-5425056-B2 | Antibody to G protein coupled receptor (GPCR) | 2007-05-15 |
| US-2010303802-A1 | Antibody directed to g protein coupled receptors (gpcr) | 2007-05-15 |
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