ReZolve-L1™ | CAS 1369583-75-4

Catalog Number	A16-0056
Category	Lipid Fluorescent Probes
Molecular Formula	C23H12N7O3Re
Molecular Weight	620.6

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Product Introduction

ReZolve-L1™ is a cell-permeable fluorogenic probe that localizes to polar lipids, and can be used to label lipid droplets and other high lipid-content compartments in live and fixed cells using fluorescent microscopy.

Chemical Information
Product Specification
Application

Synonyms	(OC-6-33)-tricarbonyl(1,10-phenanthroline-κN1,κN10)[4-(2H-tetrazol-5-yl-κN2)benzonitrilato]-rhenium
Appearance	Solid Powder

Excitation	405 nm
Emission	550 nm
Storage	Store at -20°C

ReZolve-L1™ is a fluorescent probe used in the study of cellular physiology and biochemistry. Here are some key applications of ReZolve-L1™:

Cellular Imaging: ReZolve-L1™ is employed in cellular imaging to visualize lipid droplets and track lipid metabolism within cells. By providing clear fluorescent labeling of lipid structures, researchers can study cellular lipid dynamics in various physiological and pathological contexts. This application is crucial for understanding metabolic disorders and diseases related to lipid metabolism.

Drug Delivery Research: In drug delivery studies, ReZolve-L1™ can be used to label and monitor the distribution of lipophilic drugs within biological systems. Its ability to highlight drug localization in cells helps researchers optimize drug delivery methods and improve therapeutic efficacy. This probe provides insights into the bioavailability and intracellular fate of lipid-based drug formulations.

Cancer Research: ReZolve-L1™ is utilized in cancer research to examine the role of lipid metabolism in tumor development and progression. By visualizing lipid droplet accumulation in cancer cells, scientists can investigate the metabolic adaptations that tumors undergo. This knowledge contributes to the identification of potential metabolic targets for cancer therapy and improved understanding of cancer cell biology.

Neuroscience Studies: In neuroscience, ReZolve-L1™ aids in the exploration of lipid distribution and dynamics in neuronal cells and tissues. Understanding lipid metabolism in the nervous system is essential for studying neurodegenerative diseases and brain function.