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Biotin DHPE | CAS 136235-58-0
| Catalog Number | A16-0074 |
| Category | Lipid Fluorescent Probes |
| Molecular Formula | C53H10N40O10PS |
| Molecular Weight | 1019.44 |
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
Biotin DHPE is a fluorescent probe used for labeling phospholipids and liposomes.
Chemical Information
Product Specification
Application
| Synonyms | N-(Biotinoyl)-1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine triethylammonium salt |
| Excitation | 553 |
| Emission | 575 |
Biotin DHPE is a biotinylated lipid that has significant applications in molecular biology and bioanalytical studies. Here are some key applications of Biotin DHPE:
Molecular Imaging: Biotin DHPE is often used in molecular imaging techniques to facilitate the visualization of cellular components. By incorporating Biotin DHPE into lipid bilayers, researchers can use avidin- or streptavidin-conjugated dyes for fluorescence imaging. This allows for the detailed study of membrane dynamics and cellular processes in live cells.
Protein-Lipid Interactions: Biotin DHPE is instrumental in studying protein-lipid interactions and membrane protein localization. The biotinylated lipid anchors proteins that bind to biotin, enabling researchers to investigate how specific proteins interact with lipid membranes. These studies provide insight into membrane-associated processes and can help identify potential therapeutic targets.
Affinity Purification: In bioanalytical applications, Biotin DHPE is used for affinity purification of biotin-tagged molecules. By integrating Biotin DHPE into membrane systems or liposomes, biotinylated proteins or other molecules can be captured and isolated using avidin- or streptavidin-coated columns. This method is crucial for purifying proteins for further structural and functional analyses.
Drug Delivery Research: Biotin DHPE is explored in the development of targeted drug delivery systems. By incorporating this biotinylated lipid into liposomes or nanoparticles, researchers can harness avidin-biotin interactions for the targeted delivery of therapeutic agents to specific cells or tissues.
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