Laurdan | 74515-25-6
Catelog Number | A16-0020 |
Category | Lipid Fluorescent Probes |
Molecular Formula | C24H35NO |
Molecular Weight | 353.55 |
Catalog Number | Size | Price | Quantity |
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A16-0020 | -- | $-- |
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Product Introduction
Laurdan is a fluorescent membrane probe that is sensitive to the phospholipid phase transitions of cell membrane. Quantitation of generalized polarization (GP) of laurdan can be used to identify phospholipid phase.
Chemical Information |
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Synonyms | 6-Dodecanoyl-2-dimethylaminonaphthalene; 6-Dodecanoyl-N,N-dimethyl-2-naphthylamine; N,N-Dimethyl-6-dodecanoyl-2-naphthylamine |
Purity | ≥98% |
Shelf Life | 1 Year |
IUPAC Name | 1-[6-(dimethylamino)naphthalen-2-yl]dodecan-1-one |
Canonical SMILES | CCCCCCCCCCCC(=O)C1=CC2=C(C=C1)C=C(C=C2)N(C)C |
InChI | InChI=1S/C24H35NO/c1-4-5-6-7-8-9-10-11-12-13-24(26)22-15-14-21-19-23(25(2)3)17-16-20(21)18-22/h14-19H,4-13H2,1-3H3 |
InChI Key | JHDGGIDITFLRJY-UHFFFAOYSA-N |
Solubility | Soluble in DMF, Acetonitrile, and Methanol |
Appearance | Solid Powder |
Product Specification |
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Storage | Store at -20°C |
Computed Properties | |
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XLogP3 | 8.1 |
Hydrogen Bond Donor Count | 0 |
Hydrogen Bond Acceptor Count | 2 |
Rotatable Bond Count | 12 |
Exact Mass | 353.271864740 g/mol |
Monoisotopic Mass | 353.271864740 g/mol |
Topological Polar Surface Area | 20.3Ų |
Heavy Atom Count | 26 |
Formal Charge | 0 |
Complexity | 392 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
Literatures
PMID | Publication Date | Title | Journal |
---|---|---|---|
22889622 | 2012-11-01 | Effect of the addition of alkanols of different topology to dipalmitoyl-phosphatidylcholine vesicles in the presence of gramicidin | Journal of colloid and interface science |
22522030 | 2012-10-01 | Interaction of gentamicin polycation with model and cell membranes | Bioelectrochemistry (Amsterdam, Netherlands) |
22884687 | 2012-10-01 | Use of the fluorescent probe LAURDAN to label and measure inner membrane fluidity of endospores of Clostridium spp | Journal of microbiological methods |
22555243 | 2012-05-03 | Elucidating membrane structure and protein behavior using giant plasma membrane vesicles | Nature protocols |
22406142 | 2012-04-01 | Membrane effects of lysozyme amyloid fibrils | Chemistry and physics of lipids |
Patents
Publication Number | Title | Priority Date |
---|---|---|
CN-114634553-A | Cationic peptide C9 and its application | 2022-04-27 |
WO-2022230354-A1 | Compound, fluorochrome, kit, and cell detection method | 2021-04-26 |
WO-2022204288-A1 | Branched tail lipid compounds and compositions for intracellular delivery of therapeutic agents | 2021-03-24 |
WO-2022167820-A1 | Methods for measuring the redox potential of proteins | 2021-02-08 |
WO-2022125673-A1 | Cell-penetrating peptides and peptide complexes and methods of use | 2020-12-09 |
Applications of Fluorescent Probes & Dyes
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