![{[Name]}](https://resource.bocsci.com/structure/tco-peg10-acid.gif?v=2025011501)
![{[Name]}](https://resource.bocsci.com/structure/tco-peg12-acid.gif?v=2025011501)
![{[Name]}](https://resource.bocsci.com/structure/bromoacetamido-peg3-tco.gif?v=2025011501)
![{[Name]}](https://resource.bocsci.com/structure/1191901-33-3.gif?v=2025011501)
![{[Name]}](https://resource.bocsci.com/structure/tco-peg12-amine.gif?v=2025011501)
![{[Name]}](https://resource.bocsci.com/structure/2028288-77-7.gif?v=2025011501)
Inquiry Basket
TCO-PEG36-acid
| Catalog Number | R15-0029 |
| Category | Trans Cyclooctene (TCO) |
| Molecular Formula | C₈₄H₁₆₃NO₄₀ |
| Molecular Weight | 1827.18 |
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
TCO-PEG36-acid is a polyethylene glycol (PEG)-based PROTAC linker. TCO-PEG36-acid can be used in the synthesis of a series of PROTACs.
Chemical Information
Product Specification
Application
Computed Properties
| Purity | 95% |
| IUPAC Name | 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[[(4Z)-cyclooct-4-en-1-yl]oxycarbonylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid |
| Canonical SMILES | C1CC=CCCC(C1)OC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O |
| InChI | InChI=1S/C84H163NO40/c86-83(87)8-10-89-12-14-91-16-18-93-20-22-95-24-26-97-28-30-99-32-34-101-36-38-103-40-42-105-44-46-107-48-50-109-52-54-111-56-58-113-60-62-115-64-66-117-68-70-119-72-74-121-76-78-123-80-81-124-79-77-122-75-73-120-71-69-118-67-65-116-63-61-114-59-57-112-55-53-110-51-49-108-47-45-106-43-41-104-39-37-102-35-33-100-31-29-98-27-25-96-23-21-94-19-17-92-15-13-90-11-9-85-84(88)125-82-6-4-2-1-3-5-7-82/h1-2,82H,3-81H2,(H,85,88)(H,86,87)/b2-1- |
| InChIKey | XODRNEMODIMODD-UPHRSURJSA-N |
| Solubility | DMSO, DMF, DCM |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
TCO-PEG36-acid, a versatile bifunctional molecule, finds diverse applications in bioconjugation and drug delivery. Here are four key applications:
Drug Delivery Systems: Utilizing TCO-PEG36-acid, researchers can intricately link therapeutic agents to specific targeting molecules, elevating drug delivery precision and effectiveness. By tethering drugs to the TCO-PEG36-acid linker, controlled release mechanisms are enabled, leading to improved disease site targeting. This strategy not only optimizes drug bioavailability but also mitigates potential side effects, revolutionizing treatment outcomes.
Bioconjugation Techniques: In the realm of bioconjugation, TCO-PEG36-acid emerges as a pivotal linker for amalgamating diverse biomolecules. Its multifaceted nature facilitates the connection of various biochemical entities like enzymes, antibodies, and peptides, fostering the creation of multifunctional diagnostics and therapeutics. This capability opens new avenues for innovative biomedical applications, pushing the boundaries of research possibilities.
Biomedical Imaging: Within biomedical imaging, TCO-PEG36-acid plays an indispensable role in enhancing the visualization of biological processes within the body. By conjugating imaging agents with TCO-PEG36-acid, researchers achieve targeted delivery and prolonged circulation of imaging probes, heightening the sensitivity and resolution of imaging techniques such as MRI and PET scans. This advancement in imaging technology promises enhanced diagnostic capabilities and deeper insights into physiological phenomena.
Surface Modification: TCO-PEG36-acid’s utility extends to modifying the surface properties of nanoparticles and other delivery systems, bolstering particle stability, dispersibility, and biocompatibility. This surface adaptation enhances targeted delivery applications, particularly in fields like cancer therapy and immunotherapy. By leveraging TCO-PEG36-acid for surface functionalization, researchers can optimize the efficacy and specificity of therapeutic interventions, marking a significant stride in personalized medicine approaches.
| XLogP3 | -3.6 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 40 |
| Rotatable Bond Count | 113 |
| Exact Mass | 1826.0751390 g/mol |
| Monoisotopic Mass | 1826.0751390 g/mol |
| Topological Polar Surface Area | 408Ų |
| Heavy Atom Count | 125 |
| Formal Charge | 0 |
| Complexity | 1870 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 1 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
Recommended Services
Recommended Articles
- Hoechst Dyes: Definition, Structure, Mechanism and Applications
- Mastering the Spectrum: A Comprehensive Guide to Cy3 and Cy5 Dyes
- Fluorescent Probes: Definition, Structure, Types and Application
- Fluorescent Dyes: Definition, Mechanism, Types and Application
- Coumarin Dyes: Definition, Structure, Benefits, Synthesis and Uses
- BODIPY Dyes: Definition, Structure, Synthesis and Uses
- Cyanine Dyes: Definition, Structure, Types and Uses
- Fluorescein Dyes: Definition, Structure, Synthesis and Uses
- Rhodamine Dyes: Definition, Structure, Uses, Excitation and Emission
- Unlocking the Power of Fluorescence Imaging: A Comprehensive Guide
- Cell Imaging: Definitions, Systems, Protocols, Dyes, and Applications
- Lipid Staining: Definition, Principles, Methods, Dyes, and Uses
- Flow Cytometry: Definition, Principles, Protocols, Dyes, and Uses
- Nucleic Acid Staining: Definition, Principles, Dyes, Procedures, and Uses
- DNA Staining: Definition, Procedures, Benefits, Dyes and Uses
- Cell Staining: Definition, Principles, Protocols, Dyes, and Uses
- Ion Imaging: Definition, Principles, Benefits, Dyes, and Uses
- Fluorescent Labeling: Definition, Principles, Types and Applications
Recommended Products
Online Inquiry
