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TAMRA NHS ester, 6-isomer | CAS 1027512-41-9
| Catalog Number | F07-0055 |
| Category | NHS Esters |
| Molecular Formula | C29H25N3O7 |
| Molecular Weight | 527.52 |
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Product Introduction
TAMRA NHS ester, 6-isomer is a fluorescent labeling reagent used for bioconjugation. It contains a 6-carboxytetramethylrhodamine (6-TAMRA) fluorophore activated as an N-hydroxysuccinimide (NHS) ester. The NHS ester group reacts with primary amines to form stable amide bonds, enabling efficient labeling of proteins, peptides, antibodies, and amino-modified oligonucleotides. It is widely used in fluorescence microscopy, flow cytometry, immunohistochemistry, and other molecular biology applications.
Chemical Information
Chemical Information
| Synonyms | 2-(6-Tetramethylrhodamine)carboxylic Acid N-Hydroxysuccinimide Ester; 3',6'-Bis(dimethylamino)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylic Acid 2,5-Dioxo-1-pyrrolidinyl Ester; 1-{[3',6'-Bis(dimethylamino)-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-6-carbonyl]oxy}pyrrolidine-2,5-dione; 2,5-Dioxopyrrolidin-1-yl 3',6'-bis(dimethylamino)-3-oxo-3H-spiro[[2]benzofuran-1,9'-xanthene]-6-carboxylate; 2,5-Dioxopyrrolidin-1-yl 3',6'-bis(dimethylamino)-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-6-carboxylate; NHS-6-Carboxyrhodamine; 6-Carboxytetramethylrhodamine N-hydroxysuccinimide ester; 6-TAMRA NHS |
| Purity | ≥95% |
| IUPAC Name | (2,5-dioxopyrrolidin-1-yl) 3',6'-bis(dimethylamino)-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-carboxylate |
| SMILES | CN(C)C1=CC2=C(C=C1)C3(C4=C(O2)C=C(C=C4)N(C)C)C5=C(C=CC(=C5)C(=O)ON6C(=O)CCC6=O)C(=O)O3 |
| InChI | InChI=1S/C29H25N3O7/c1-30(2)17-6-9-20-23(14-17)37-24-15-18(31(3)4)7-10-21(24)29(20)22-13-16(5-8-19(22)28(36)38-29)27(35)39-32-25(33)11-12-26(32)34/h5-10,13-15H,11-12H2,1-4H3 |
| InChIKey | LVKNGXYHCROLAQ-UHFFFAOYSA-N |
| Solubility | Soluble in Acetonitrile (Slightly), DMSO (Slightly) |
| Density | 1.49±0.1 g/cm3 |
| Appearance | Black solid |
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