DBCO-C6-acid | 1425485-72-8

DBCO-C6-acid, a chemical compound prevalent in bioorthogonal chemistry and molecular imaging, boasts diverse applications in the scientific realm. Here, we delve into four key applications of DBCO-C6-acid:

Bioconjugation: Within bioconjugation techniques, DBCO-C6-acid emerges as a pivotal player, facilitating the attachment of biomolecules like proteins, peptides, or nucleic acids to various substrates. Leveraging the specific reactivity between DBCO and azide groups, researchers can forge stable and precise bioconjugates. This application serves as a linchpin in devising targeted drug delivery systems and diagnostic tools.

Molecular Imaging: In the realm of molecular imaging, DBCO-C6-acid finds utility in labeling biomolecules with imaging agents, enhancing the visualization of intricate biological processes. The DBCO moiety streamlines the conjugation of fluorescent dyes or radioactive isotopes to molecules of interest, enabling real-time monitoring of biological phenomena in vivo.

Cell Surface Engineering: A key player in cell surface engineering, DBCO-C6-acid transforms the landscape of living cell modification by imparting functional moieties onto cellular surfaces. By introducing azide-labeled molecules to cell surfaces, DBCO-C6-acid enables the subsequent attachment of diverse probes and ligands.

Click Chemistry: DBCO-C6-acid stands as an indispensable reagent in the realm of click chemistry, a potent and efficient chemical reaction utilized across various research domains. Through the strain-promoted azide-alkyne cycloaddition (SPAAC) reaction between DBCO and azides, researchers achieve rapid and bioorthogonal formation of covalent bonds. This application finds widespread use in synthesizing complex biomolecules, advancing drug development, and pushing the boundaries of materials science, underscoring its pivotal role in scientific innovation.