Biotin-PEG4-NHS ester | CAS 459426-22-3

Name: Biotin-PEG4-NHS ester
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog Number	R01-0474
Category	NHS Esters
Molecular Formula	C25H40N4O10S
Molecular Weight	588.67

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Product Introduction

Biotin-PEG4-NHS ester is a heterobifunctional reagent that features a biotin moiety linked to an NHS ester through a polyethylene glycol (PEG) spacer. This compound is designed for efficient bioconjugation, enabling the covalent attachment of biotin to primary amines on proteins, peptides, or other biomolecules via the NHS ester group. The PEG4 spacer imparts increased solubility and flexibility, facilitating the biotinylation process in various labeling and surface modification applications, particularly in the context of affinity purification and detection assays.

Chemical Information
Product Specification

Chemical Information

Synonyms	3-[2-[2-[2-[2-[[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid (2,5-dioxo-1-pyrrolidinyl) ester; (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
Purity	>97%
IUPAC Name	(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
SMILES	C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCNC(=O)CCCCC2C3C(CS2)NC(=O)N3
InChI	InChI=1S/C25H40N4O10S/c30-20(4-2-1-3-19-24-18(17-40-19)27-25(34)28-24)26-8-10-36-12-14-38-16-15-37-13-11-35-9-7-23(33)39-29-21(31)5-6-22(29)32/h18-19,24H,1-17H2,(H,26,30)(H2,27,28,34)/t18-,19-,24-/m0/s1
InChIKey	DTLVBHCSSNJCMJ-JXQFQVJHSA-N
Solubility	In DMSO: 125 mg/mL (212.34 mM; Need ultrasonic)
Density	1.3±0.1 g/cm3
Appearance	Solid powder
LogP	0.87850