BCN-PEG3-Biotin (exo)

Product Introduction

BCN-PEG3-Biotin (exo) is a bioconjugation reagent that features a bicyclo[6.1.0]nonyne (BCN) moiety, which is known for its participation in strain-promoted azide-alkyne cycloaddition (SPAAC) reactions. The incorporation of a triethylene glycol (PEG3) spacer enhances solubility and flexibility, facilitating efficient biotinylation of biomolecules or surfaces without interfering with biological activity. Biotin, a well-established affinity tag, allows for subsequent interaction with streptavidin or avidin, enabling diverse applications in molecular labeling, affinity purification, and detection assays within the realms of click chemistry and bioorthogonal conjugation strategies.