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7-Amino-4-methylquinolin-2(1H)-one | CAS 19840-99-4
| Catalog Number | A17-0041 |
| Category | Laser Dyes |
| Molecular Formula | C10H10N2O |
| Molecular Weight | 174.20 |
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Product Introduction
7-Amino-4-methylquinolin-2(1H)-one is a heterocyclic compound featuring a quinoline core structure, which is integral to its chromophore properties. The presence of an amino group at the 7-position and a methyl group at the 4-position contributes to its unique spectral characteristics, enabling its use in fluorescence-based assays and imaging applications. This compound is often incorporated into molecular probes and fluorescent labels, supporting various research contexts such as nucleic acid labeling and intracellular imaging due to its ability to engage in specific conjugation reactions with biomolecules.
Chemical Information
Application
Chemical Information
| Synonyms | Carbostyril 124;7-amino-4-methyl-1H-quinolin-2-one; 7-amino-4-methyl-1H-quinolin-2-one |
| IUPAC Name | 7-amino-4-methyl-1H-quinolin-2-one |
| SMILES | CC1=CC(=O)NC2=C1C=CC(=C2)N |
| InChI | InChI=1S/C10H10N2O/c1-6-4-10(13)12-9-5-7(11)2-3-8(6)9/h2-5H,11H2,1H3,(H,12,13) |
| InChIKey | MJXYFLJHTUSJGU-UHFFFAOYSA-N |
| Density | 1.223 g/cm3 |
| Appearance | Off-white to light beige solid |
| Boiling Point | 417.6 °C at 760 mmHg |
| Melting Point | >270 °C (dec.) |
| LogP | 2.41220 |
Application
7-Amino-4-methylquinolin-2(1H)-one, a versatile organic compound, finds significant applications in diverse bioscience fields.
Pharmaceutical Research: Serving as a valuable scaffold for new therapeutic agents, 7-Amino-4-methylquinolin-2(1H)-one stands at the forefront of drug discovery. Its distinctive quinoline structure positions it as an ideal candidate for combating bacterial infections and cancer. Researchers delve into its modifications, seeking to amplify biological activity while mitigating potential side effects, propelling the realm of pharmaceutical innovation.
Chemical Synthesis: Operating as a pivotal intermediate in molecular synthesis, this compound plays a crucial role in generating complex molecules. Frequently utilized in crafting heterocyclic compounds and other pharmacologically active agents, it offers chemists a canvas to introduce diverse functional groups, yielding derivatives with a wide array of chemical properties and prospective applications.
Fluorescent Probes: The inherent fluorescent characteristics of 7-Amino-4-methylquinolin-2(1H)-one render it an indispensable asset in the realm of fluorescent probe development. These probes, integral to various imaging methodologies, illuminate cellular components and biological processes, affording researchers a real-time glimpse into cellular dynamics, protein interactions, and other phenomena.
Biochemical Assays: Versatile in its application, 7-Amino-4-methylquinolin-2(1H)-one emerges as a critical substrate and reagent in biochemical assays. Its reactive nature enables participation in enzymatic reactions, facilitating the detection of specific enzyme activities. These assays play a pivotal role in diagnostics, drug screening, and enzymology research, offering invaluable insights into the biochemical underpinnings of biological systems.
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