4-Methylumbelliferyl 6-thio-Palmitate-β-D-Glucopyranoside | 229644-17-1
Catelog Number | A18-0100 |
Category | Fluorescent Enzyme Substrates |
Molecular Formula | C32H48O8S |
Molecular Weight | 592.78 |
Catalog Number | Size | Price | Quantity |
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A18-0100 | -- | $-- |
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Product Introduction
4-Methylumbelliferyl 6-thio-palmitate-β-D-glucopyranoside is a fluorogenic substrate for palmitoyl-protein thioesterase (PPT), a lysosomal hydrolase that removes long-chain fatty acyl groups from modified cysteine residues in proteins. It is cleaved by PPT to produce fluorescent moiety 4-MU. It can be used in the diagnosis of infantile neuronal ceroid lipofuscinosis (INCL).
Chemical Information |
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Synonyms | Mu-6S-Palm-β-Glc; 4-methyl-7-[[6-S-(1-oxohexadecyl)-6-thio-β-D-glucopyranosyl]oxy]-2H-1-benzopyran-2-one |
Purity | ≥95% |
IUPAC Name | S-[[(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(4-methyl-2-oxochromen-7-yl)oxyoxan-2-yl]methyl] hexadecanethioate |
Canonical SMILES | CCCCCCCCCCCCCCCC(=O)SCC1C(C(C(C(O1)OC2=CC3=C(C=C2)C(=CC(=O)O3)C)O)O)O |
InChI | InChI=1S/C32H48O8S/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-28(34)41-21-26-29(35)30(36)31(37)32(40-26)38-23-17-18-24-22(2)19-27(33)39-25(24)20-23/h17-20,26,29-32,35-37H,3-16,21H2,1-2H3/t26?,29-,30+,31-,32-/m1/s1 |
InChI Key | XCNUAQFXJPMZLU-BPXMXZQQSA-N |
Appearance | White to Off-white Solid |
Melting Point | 123-125°C |
Product Specification |
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Storage | Store at -20°C |
Applications of Fluorescent Probes & Dyes
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