Monodansylcadaverine

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Monodansylcadaverine

Monodansylcadaverine | CAS 10121-91-2

Catalog Number A16-0028
Category Lipid Fluorescent Probes
Molecular Formula C17H25N3O2S
Molecular Weight 335.5
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Product Introduction

Monodansylcadaverine (MDC) is a fluorescent probe that is used for detecting autophagy in the cytoplasm and vacuoles of plants and mammalian cells via marking the autophagosomes. Study revealed that monodansylcadaverine acts as a lysosomotropic agent, being concentrated into acidic compartments by an ion-trapping mechanism, and as a solvent polarity probe, increasing its relative fluorescence intensity by interacting with membrane lipids that are highly concentrated in the autophagic vacuoles.

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  • Application

Synonyms Dansylcadaverine; MDC; N-(5-aminopentyl)-5-(dimethylamino)-1-naphthalenesulfonamid
Purity ≥95%
Canonical SMILES CN(C)C1=CC=CC2=C1C=CC=C2S(=O)(=O)NCCCCCN
InChI InChI=1S/C17H25N3O2S/c1-20(2)16-10-6-9-15-14(16)8-7-11-17(15)23(21,22)19-13-5-3-4-12-18/h6-11,19H,3-5,12-13,18H2,1-2H3
InChIKey MLEBFEHOJICQQS-UHFFFAOYSA-N
Appearance Solid Powder
Storage Store at -20°C

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