MitoMark Red I

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MitoMark Red I

MitoMark Red I | 167095-09-2

Catalog Number A16-0007
Category Mitochondrial Fluorescent Probes
Molecular Formula C32H32Cl2N2O
Molecular Weight 531.52
Catalog Number Size Price Quantity
A16-0007 -- $--

Product Introduction

MitoMark Red I is a red fluorescent mitochondrial stain.

Chemical Information

Synonyms 9-[4-(Chloromethyl)phenyl]-2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-xantheno[2,3,4-ij:5,6,7-i'j']diquinolizin-18-ium chloride; MitoTracker Red; MTRed; CMXRos; Chloromethyl-X-rosamine
Purity ≥90% by HPLC
IUPAC Name 16-[4-(chloromethyl)phenyl]-3-oxa-23-aza-9-azoniaheptacyclo[17.7.1.15,9.02,17.04,15.023,27.013,28]octacosa-1(27),2(17),4,9(28),13,15,18-heptaene;chloride
Canonical SMILES C1CC2=C3C(=C4C(=C2)C(=C5C=C6CCC[N+]7=C6C(=C5O4)CCC7)C8=CC=C(C=C8)CCl)CCCN3C1.[Cl-]
InChI InChI=1S/C32H32ClN2O.ClH/c33-19-20-9-11-21(12-10-20)28-26-17-22-5-1-13-34-15-3-7-24(29(22)34)31(26)36-32-25-8-4-16-35-14-2-6-23(30(25)35)18-27(28)32;/h9-12,17-18H,1-8,13-16,19H2;1H/q+1;/p-1
InChI Key IKEOZQLIVHGQLJ-UHFFFAOYSA-M
  • Product Specification
  • Application
Storage Store at -20°C

MitoMark Red I, a specialized fluorescent dye tailored for mitochondria labeling in live cell imaging, finds diverse applications in scientific research. Here are four key applications of MitoMark Red I:

Live Cell Imaging: In the realm of live cell imaging, MitoMark Red I emerges as a crucial tool for tracking and studying mitochondria dynamics in real-time. By facilitating the visualization of processes like fission, fusion, and cellular movement, researchers gain valuable insights into the intricate functioning and health of mitochondria across various cellular contexts and pathological states.

Apoptosis Studies: Delving into apoptosis exploration, MitoMark Red I shines as it aids in the detection of alterations in mitochondrial membrane potential—a hallmark of programmed cell death. Through the staining of mitochondria, researchers can closely monitor the early events of apoptosis, unraveling the underlying mechanisms of cell demise. This knowledge is pivotal for unraveling the intricate roles of mitochondria in diseases like cancer and neurodegeneration.

Drug Screening: Transitioning to drug screening endeavors, MitoMark Red I plays a pivotal role in high-throughput assays designed to assess the impacts of pharmaceutical compounds on mitochondrial function. By scrutinizing changes in mitochondrial morphology and functionality post-drug exposure, researchers can pinpoint potential mitochondrial toxicants or therapeutic agents with precision. This facilitates the advancement and safety assessment of novel drug candidates.

Metabolic Studies: Lastly, in the domain of metabolic research, MitoMark Red I takes center stage for its contribution to unraveling mitochondrial bioenergetics. By enabling the measurement of key parameters, such as mitochondrial respiration and ATP production under diverse experimental conditions, this dye empowers scientists to deepen their understanding of metabolic processes. Such insights are instrumental in tackling energy metabolism disorders and formulating effective therapeutic strategies for metabolic ailments.

Computed Properties

Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 3
Rotatable Bond Count 2
Exact Mass 530.1891690 g/mol
Monoisotopic Mass 530.1891690 g/mol
Topological Polar Surface Area 15.5Ų
Heavy Atom Count 37
Formal Charge 0
Complexity 995
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 2
Compound Is Canonicalized Yes

Patents

Publication NumberTitlePriority Date
KR-102480069-B1 Composition for diagnosing diabetic retinopathy using biomarkers, method for providing information for diagnosing diabetic retinopathy, and screening method for substances for treatment of diabetic retinopathy 2022-09-08
CN-115141801-A Methods, kits and uses for the analysis of different lymphocyte subsets based on mitochondrial metabolic activity 2022-08-16
CN-115232820-A Application of miR-142-3p in the treatment of high salt-induced cardiac fibrosis 2022-05-23
CN-114716635-A A kind of multifunctional polyurea acid derivative and its preparation method and application 2022-05-12
CN-114854816-A A keratinocyte exosome-mediated approach to promote hair growth 2022-05-09
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