
LYCBX
| Catalog Number | A16-0129 |
| Category | Other Cell Fluorescent Probes |
| Molecular Formula | C33H42K2N6O11S3 |
| Molecular Weight | 783.11 |
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
LYCBX is a proprietary lysosome-targeted fluorescent probe offering bright yellow emission. It’s used for live-cell lysosomal tracking and activity visualization.
Chemical Information
Product Specification
Application
Computed Properties
Chemical Information
| IUPAC Name | dipotassium;2-[5-[6-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]hexanoylamino]pentyl]-6-amino-1,3-dioxobenzo[de]isoquinoline-5,8-disulfonate |
| SMILES | C1C2C(C(S1)CCCCC(=O)NCCCCCC(=O)NCCCCCN3C(=O)C4=CC(=CC5=C4C(=CC(=C5N)S(=O)(=O)[O-])C3=O)S(=O)(=O)[O-])NC(=O)N2.[K+].[K+] |
| InChI | InChI=1S/C33H44N6O11S3.2K/c34-29-20-15-19(52(45,46)47)16-21-28(20)22(17-25(29)53(48,49)50)32(43)39(31(21)42)14-8-2-7-13-36-26(40)10-3-1-6-12-35-27(41)11-5-4-9-24-30-23(18-51-24)37-33(44)38-30;;/h15-17,23-24,30H,1-14,18,34H2,(H,35,41)(H,36,40)(H2,37,38,44)(H,45,46,47)(H,48,49,50);;/q;2*+1/p-2/t23-,24-,30-;;/m0../s1 |
| InChIKey | VZXAFTRIDBDGEE-HPIAMODPSA-L |
Product Specification
| Excitation | Lucifer Yellow (LY) |
| Emission | 812 |
Application
LYCBX is a fluorescent chemistry reagent designed for incorporation into labeling workflows where controlled fluorescence readout is needed for imaging and analytical assays. Its use in molecular staining and fluorescence-based detection is typically driven by the ability to form stable conjugates with biomolecules or to be integrated into probe constructs for microscopy and quantitative fluorescence measurements.
1. Fluorescence Labeling Conjugates
LYCBX is used by chemical biology and biomaterials researchers to generate fluorescent labeling conjugates for tracking biomolecule localization and distribution in complex samples. In protein and peptide labeling workflows, it is commonly incorporated into research-grade conjugates that are subsequently analyzed by fluorescence microscopy or fluorescence imaging systems to map relative abundance or spatial organization. In nucleic acid workflows, it can be integrated into labeled oligonucleotide constructs used for fluorescence-based readouts in assay development.
2. Microscopy Staining Workflows
LYCBX supports fluorescence microscopy staining strategies where researchers need a robust fluorescent tag for visualizing labeled targets within fixed or prepared specimens. Molecular staining teams often employ LYCBX-derived conjugates to visualize biomolecular distribution in cell-associated or biomaterial-associated contexts, enabling comparative imaging across experimental conditions. The reagent's value in microscopy workflows is tied to practical labeling compatibility with standard fluorescence imaging instrumentation used in life-science laboratories.
3. Fluorescence-Based Bioassays
LYCBX is applied in fluorescence assay development where signal generation from a labeled component is required for quantitative readout. Assay developers use LYCBX-containing conjugates as fluorescent reporters in plate-based fluorescence measurements, supporting workflow designs that rely on relative fluorescence intensity as the primary endpoint. This positioning is especially common in research settings focused on reagent screening, assay optimization, and the construction of fluorescence readout reagents for analytical biology.
4. Probe Construction For Imaging
LYCBX is leveraged in fluorescent probe development to build labeled probe constructs for downstream molecular imaging experiments. Probe engineers incorporate LYCBX into research tools intended for visualization of labeled biomolecular components, enabling experimental designs where the fluorescent tag serves as a consistent marker across different sample formats. In these workflows, LYCBX is selected for its practical utility in producing fluorescent probe reagents that can be handled in standard fluorescence imaging and analysis pipelines.
Computed Properties
| Hydrogen Bond Donor Count | 5 |
| Hydrogen Bond Acceptor Count | 13 |
| Rotatable Bond Count | 19 |
| Exact Mass | 872.1347827 g/mol |
| Monoisotopic Mass | 872.1347827 g/mol |
| Topological Polar Surface Area | 319Ų |
| Heavy Atom Count | 55 |
| Formal Charge | 0 |
| Complexity | 1600 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 3 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 3 |
| Compound Is Canonicalized | Yes |
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