
LDS 798 | CAS 92479-59-9
| Catalog Number | A17-0123 |
| Category | Laser Dyes |
| Molecular Formula | C23H25N2∙ClO4 |
| Molecular Weight | 428.913 |
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Product Introduction
LDS 798 emits in the near-infrared region, making it excellent for in vivo imaging and photoacoustic applications. It provides strong signals for tissue-level visualization.
Chemical Information
Application
Chemical Information
| Synonyms | 4-[4-[4-(dimethylamino)phenyl]-1,3-butadienyl]-1-ethyl quinolinium perchlorate; Styryl 11 |
| SMILES | CC[N+]1=CC=C(C2=CC=CC=C21)C=CC=CC3=CC=C(C=C3)N(C)C.[O-]Cl(=O)(=O)=O |
| InChI | InChI=1S/C23H25N2.ClHO4/c1-4-25-18-17-20(22-11-7-8-12-23(22)25)10-6-5-9-19-13-15-21(16-14-19)24(2)3;2-1(3,4)5/h5-18H,4H2,1-3H3;(H,2,3,4,5)/q+1;/p-1 |
| InChIKey | BLOOIVHLHVECMY-UHFFFAOYSA-M |
Application
LDS 798 is a fluorescent dye used as a molecular labeling and imaging reagent, typically in the far-red to near-infrared region, enabling low-background visualization in fluorescence workflows. Its labeling-oriented chemistry supports conjugation to biomolecules and incorporation into staining and tracking formats where bright emission and convenient detection are required, including multicolor imaging strategies that benefit from reduced spectral overlap.
1. Fluorescence Microscopy Labeling
LDS 798 is used by cell biology and materials researchers to generate far-red fluorescent labeling for microscopy studies of biomolecules, polymers, and labeled probes in fixed-cell or prepared sample formats. In practice, it is commonly incorporated into conjugates for tracking distribution in cellular imaging experiments, where its emission in the red/far-red window supports visualization alongside other fluorophores. Researchers also use LDS 798-labeled reagents to follow adsorption, retention, or localization of fluorescent tags on engineered surfaces and biomaterial constructs during imaging readouts.
2. Flow Cytometry Fluorescent Tagging
LDS 798 is applied in flow cytometry workflows as a fluorescent tag for labeling biomolecules, affinity reagents, or labeled populations prior to analysis. Its far-red spectral behavior makes it useful for multicolor panel development when spectral separation from common green/orange channels is needed. Typical users include immunology and cell-sorting laboratories that prepare fluorescent conjugates for staining workflows and then quantify labeled targets by fluorescence intensity in instrument-compatible detection channels.
3. Fluorescent Bioassay Tracing
LDS 798 is frequently used in fluorescence-based bioassay development as a tracer dye for monitoring binding, transport, or incorporation events in assay formats where a stable far-red readout is advantageous. Assay developers use LDS 798-containing conjugates to visualize reagent uptake, track labeled components in wash steps, or generate fluorescence signals that report on process completion in plate-based experiments. This makes the dye relevant to chemical biology screening and assay optimization efforts that rely on robust fluorescence detection rather than target-specific recognition.
4. Polymer And Surface Functionalization
LDS 798 is used to prepare fluorescently labeled polymers, coatings, and functional materials for studying surface interactions and material behavior under experimental conditions. Materials scientists incorporate the dye into polymer labeling strategies to enable visualization of film formation, surface coverage, or diffusion-like distribution patterns in imaging experiments. In addition, LDS 798-labeled materials are commonly used to confirm successful functionalization of substrates and to support downstream characterization by fluorescence microscopy and related optical readouts.
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