JC-1
- Catelog Number: A16-0011
- Category: Mitochondrial Fluorescent Probes
JC-1 is a cyanine dye used for studying mitochondrial integrity in the context of cellular apoptosis. JC-1 exhibits green fluorescence at low membrane potential and aggregates to exhibit red fluorescence at higher membrane potentials.
| Chemical Information | |
|---|---|
| Catelog Number: | A16-0011 |
| Product Name: | JC-1 |
| CAS Number: | 3520-43-2 |
| Molecular Formula: | C25H27Cl4IN4 |
| Molecular Weight: | 652.2 |
| Purity: | ≥90% |
| Synonyms: | 5,6-dichloro-2-[3-(5,6-dichloro-1,3-diethyl-1,3-dihydro-2H-benzimidazol-2-ylidene)-1-propen-1-yl]-1,3-diethyl-1H-benzimidazolium, monoiodide; CBIC2; NK 1420 |
| Product Specification | |
|---|---|
| Appearance: | Solid Powder |
| Storage Conditions: | Store at -20°C |
| Excitation Maximum (nm): | 485 (monomer), 520-570 (aggregate) |
| Emission Maximum (nm): | 535 (monomer), 570-610 (aggregate) |
| Additional Information | |
|---|---|
| InChI: | InChI=1S/C25H27Cl4N4.HI/c1-5-30-20-12-16(26)17(27)13-21(20)31(6-2)24(30)10-9-11-25-32(7-3)22-14-18(28)19(29)15-23(22)33(25)8-4;/h9-15H,5-8H2,1-4H3;1H/q+1;/p-1 |
| InChIKey: | FYNNIUVBDKICAX-UHFFFAOYSA-M |
| CanonicalSMILES: | CCN1C2=CC(=C(C=C2[N+](=C1C=CC=C3N(C4=CC(=C(C=C4N3CC)Cl)Cl)CC)CC)Cl)Cl.[I-] |
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