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IR-797 Chloride | 110992-55-7
| Catalog Number | A17-0010 |
| Category | Laser Dyes |
| Molecular Formula | C31H34Cl2N2 |
| Molecular Weight | 505.53 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| A17-0010 | -- | $-- |
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Product Introduction
IR-797 chloride is a methanol-soluble dye that can be used as a laser dye and as a near-IR dye.
Chemical Information |
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|---|---|
| Related CAS | 69415-29-8 (free base) |
| Synonyms | 2-[2-[2-chloro-3-[2-(1,3,3-trimethylindol-1-ium-2-yl)ethenyl]cyclopent-2-en-1-ylidene]ethylidene]-1,3,3-trimethylindole chloride |
| Canonical SMILES | CC1(C2=CC=CC=C2[N+](=C1C=CC3=C(C(=CC=C4C(C5=CC=CC=C5N4C)(C)C)CC3)Cl)C)C.[Cl-] |
| InChI | InChI=1S/C31H34ClN2.ClH/c1-30(2)23-11-7-9-13-25(23)33(5)27(30)19-17-21-15-16-22(29(21)32)18-20-28-31(3,4)24-12-8-10-14-26(24)34(28)6;/h7-14,17-20H,15-16H2,1-6H3;1H/q+1;/p-1 |
| InChI Key | OATKVFFCVUJOEX-UHFFFAOYSA-M |
| Appearance | Solid Powder |
- Product Specification
- Application
| Excitation | 603 |
| Emission | 625 |
IR-797 Chloride, a prominent near-infrared fluorescent dye, is extensively utilized in various bioscience applications. Here are four key applications of IR-797 Chloride presented:
Molecular Imaging: Positioned at the cutting edge of molecular imaging, IR-797 Chloride plays a pivotal role in visualizing and monitoring biological phenomena within living organisms. Its near-infrared fluorescence enables deep tissue penetration and minimizes background interference, making it an optimal choice for applications such as tumor imaging, vascular mapping, and tracking targeted drug delivery in vivo.
Cell Labeling: Unveiling the intricacies of cell biology, IR-797 Chloride serves as a versatile tool for labeling cells in culture, facilitating the observation of cell behaviors such as proliferation, migration, and differentiation. The fluorescent properties of the dye enable researchers to monitor labeled cells over time while mitigating phototoxic effects. This capability is particularly invaluable in fields like stem cell research, cancer studies, and immunology, where precise cell tracking is essential.
Photothermal Therapy: Embarking on innovative cancer treatment strategies, IR-797 Chloride stands out as a crucial component in photothermal therapy, acting as a potent photosensitizer. By converting light energy into heat, it can selectively target and eliminate cancer cells. Upon exposure to near-infrared light, it triggers localized hyperthermia, leading to the demise of malignant tissues. This non-invasive approach demonstrates tremendous potential in preclinical trials for combating a diverse array of tumors.
Diagnostics: Spearheading diagnostic advancements, IR-797 Chloride enhances the sensitivity and specificity of detection methods in assays. Through conjugation with antibodies or other biomolecules, it gives rise to fluorescent probes capable of detecting specific biomarkers with precision. These probes are instrumental in cutting-edge techniques like flow cytometry, western blotting, and immunofluorescence microscopy, delivering accurate and dependable diagnostic outcomes.
Applications of Fluorescent Probes & Dyes
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