Hexamethylindotricarbocyanine perchlorate | CAS 16595-48-5

Catalog Number	A17-0025
Category	Laser Dyes
Molecular Formula	C29H33ClN2O4
Molecular Weight	509.04

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Product Introduction

Hexamethylindotricarbocyanine perchlorate is a long-wavelength, membrane-potential sensitive dye. It is a slow-response potentiometric fluorophore and has also been used as a laser dye for infrared lasers.

Chemical Information
Application

Synonyms	2-[7-(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)-1,3,5-heptatrienyl]-1,3,3-trimethyl-3H-indolium perchlorate; 1,1',3,3,3',3'-hexamethyl-2,2'-indotricarbocyanine perchlorate
Canonical SMILES	CC1(C2=CC=CC=C2[N+](=C1C=CC=CC=CC=C3C(C4=CC=CC=C4N3C)(C)C)C)C.[O-]Cl(=O)(=O)=O
InChI	InChI=1S/C29H33N2.ClHO4/c1-28(2)22-16-12-14-18-24(22)30(5)26(28)20-10-8-7-9-11-21-27-29(3,4)23-17-13-15-19-25(23)31(27)6;2-1(3,4)5/h7-21H,1-6H3;(H,2,3,4,5)/q+1;/p-1
InChIKey	NHQOULZCPKJYMM-UHFFFAOYSA-M
Appearance	Solid Powder

Hexamethylindotricarbocyanine perchlorate is a fluorescent dye widely used in various scientific disciplines. Here are some key applications of Hexamethylindotricarbocyanine perchlorate:

Live Cell Imaging: This dye is extensively used in live cell imaging due to its high fluorescence intensity and photostability. Researchers employ it to stain cellular structures and organelles, allowing detailed observation of cellular processes in real-time. This facilitates studies on cell morphology, dynamics, and interactions under various conditions.

Flow Cytometry: Hexamethylindotricarbocyanine perchlorate is crucial in flow cytometry for labeling cells and analyzing their characteristics. Its strong fluorescence enables the detection and quantification of specific cell populations in a mixed sample. This application is essential for immunophenotyping, cell sorting, and studying cellular responses to treatments.

Molecular Probes: The dye is used as a molecular probe in studying biological molecules and their interactions. It can be conjugated to antibodies, nucleic acids, or other biomolecules to track their location and binding activities. This allows for the detailed analysis of molecular pathways and mechanisms in various biological systems.

Diagnostic Imaging: Hexamethylindotricarbocyanine perchlorate is utilized in diagnostic imaging techniques, including near-infrared fluorescence imaging. Its ability to penetrate tissues and emit in the near-infrared range makes it ideal for non-invasive imaging of tissues and organs. This enhances the capabilities of medical imaging for early diagnosis and treatment monitoring.