DISBAC10

What We Offer

DISBAC10

DISBAC10 | 169211-45-4

Catelog Number A16-0031
Category Cell membrane Fluorescent Probes
Molecular Formula C51H88N4O4S2
Molecular Weight 885.4
Catalog Number Size Price Quantity
A16-0031 -- $--

Product Introduction

DISBAC10 is a voltage-sensitive fluorescent probe used to study cell membrane electrical activity in FRET assays. In a resting polarized cell, DISBAC10 resides on the outer leaflet of the membrane where it accepts photons from excited fluorescein-labeled proteins and re-emits the photons at a higher wavelength. Depolarization of the cell causes rapid translocation of DISBAC10 to the inner leaflet of the membrane, thereby increasing the distance between fluorophores and reducing the FRET signal.

Chemical Information

Synonyms 1,3-didecyl-5-[3-(1,3-didecylhexahydro-4,6-dioxo-2-thioxo-5-pyrimidinyl)-2-propenylidene]dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione
Purity ≥98%
IUPAC Name 1,3-didecyl-5-[3-(1,3-didecyl-4,6-dioxo-2-sulfanylidene-1,3-diazinan-5-yl)prop-2-enylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione
Canonical SMILES CCCCCCCCCCN1C(=O)C(C(=O)N(C1=S)CCCCCCCCCC)C=CC=C2C(=O)N(C(=S)N(C2=O)CCCCCCCCCC)CCCCCCCCCC
InChI InChI=1S/C51H90N4O4S2/c1-5-9-13-17-21-25-29-33-40-52-46(56)44(47(57)53(50(52)60)41-34-30-26-22-18-14-10-6-2)38-37-39-45-48(58)54(42-35-31-27-23-19-15-11-7-3)51(61)55(49(45)59)43-36-32-28-24-20-16-12-8-4/h37-39,44,46,56H,5-36,40-43H2,1-4H3/b38-37+
InChI Key XDRMUCPEPWWVLX-HEFFKOSUSA-N

Product Specification

Excitation 540 nm
Emission 560 nm
Storage Store at -20°C

Computed Properties

XLogP3 18.5
Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 6
Rotatable Bond Count 38
Exact Mass 884.62469965 g/mol
Monoisotopic Mass 884.62469965 g/mol
Topological Polar Surface Area 145Ų
Heavy Atom Count 61
Formal Charge 0
Complexity 1260
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 1
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes
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