DISBAC10 | 169211-45-4
Catelog Number | A16-0031 |
Category | Cell membrane Fluorescent Probes |
Molecular Formula | C51H88N4O4S2 |
Molecular Weight | 885.4 |
Catalog Number | Size | Price | Quantity |
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A16-0031 | -- | $-- |
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Product Introduction
DISBAC10 is a voltage-sensitive fluorescent probe used to study cell membrane electrical activity in FRET assays. In a resting polarized cell, DISBAC10 resides on the outer leaflet of the membrane where it accepts photons from excited fluorescein-labeled proteins and re-emits the photons at a higher wavelength. Depolarization of the cell causes rapid translocation of DISBAC10 to the inner leaflet of the membrane, thereby increasing the distance between fluorophores and reducing the FRET signal.
Chemical Information |
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Synonyms | 1,3-didecyl-5-[3-(1,3-didecylhexahydro-4,6-dioxo-2-thioxo-5-pyrimidinyl)-2-propenylidene]dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione |
Purity | ≥98% |
IUPAC Name | 1,3-didecyl-5-[3-(1,3-didecyl-4,6-dioxo-2-sulfanylidene-1,3-diazinan-5-yl)prop-2-enylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione |
Canonical SMILES | CCCCCCCCCCN1C(=O)C(C(=O)N(C1=S)CCCCCCCCCC)C=CC=C2C(=O)N(C(=S)N(C2=O)CCCCCCCCCC)CCCCCCCCCC |
InChI | InChI=1S/C51H90N4O4S2/c1-5-9-13-17-21-25-29-33-40-52-46(56)44(47(57)53(50(52)60)41-34-30-26-22-18-14-10-6-2)38-37-39-45-48(58)54(42-35-31-27-23-19-15-11-7-3)51(61)55(49(45)59)43-36-32-28-24-20-16-12-8-4/h37-39,44,46,56H,5-36,40-43H2,1-4H3/b38-37+ |
InChI Key | XDRMUCPEPWWVLX-HEFFKOSUSA-N |
Product Specification |
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Excitation | 540 nm |
Emission | 560 nm |
Storage | Store at -20°C |
Computed Properties | |
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XLogP3 | 18.5 |
Hydrogen Bond Donor Count | 0 |
Hydrogen Bond Acceptor Count | 6 |
Rotatable Bond Count | 38 |
Exact Mass | 884.62469965 g/mol |
Monoisotopic Mass | 884.62469965 g/mol |
Topological Polar Surface Area | 145Ų |
Heavy Atom Count | 61 |
Formal Charge | 0 |
Complexity | 1260 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 1 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
Applications of Fluorescent Probes & Dyes
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