Di-8-ANEPPS

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Di-8-ANEPPS

Di-8-ANEPPS | 157134-53-7

Catelog Number A16-0026
Category Mitochondrial Fluorescent Probes
Molecular Formula C36H52N2O3S
Molecular Weight 592.9
Catalog Number Size Price Quantity
A16-0026 -- $--

Product Introduction

Di-8-ANEPPS is a fast-responding membrane potential dye. It produces strong fluorescence when bound to the lipid bilayer (ex/em max = ~467/631 nm). The fluorescence intensity of di-8-ANEPPS varies proportionally to changes in transmembrane voltage, therefore it is an ideal probe for measuring membrane voltage.

Chemical Information

Synonyms 4-[2-[6-(dioctylamino)-2-naphthalenyl]ethenyl]-1-(3-sulfopropyl)-pyridinium, inner salt
Purity ≥98%
IUPAC Name 3-[4-[(E)-2-[6-(dioctylamino)naphthalen-2-yl]ethenyl]pyridin-1-ium-1-yl]propane-1-sulfonate
Canonical SMILES CCCCCCCCN(CCCCCCCC)C1=CC2=C(C=C1)C=C(C=C2)C=CC3=CC=[N+](C=C3)CCCS(=O)(=O)[O-]
InChI InChI=1S/C36H52N2O3S/c1-3-5-7-9-11-13-25-38(26-14-12-10-8-6-4-2)36-21-20-34-30-33(18-19-35(34)31-36)17-16-32-22-27-37(28-23-32)24-15-29-42(39,40)41/h16-23,27-28,30-31H,3-15,24-26,29H2,1-2H3
InChI Key IXFSUSNUALIXLU-UHFFFAOYSA-N
Appearance Solid Powder

Product Specification

Excitation 467 nm
Emission 631 nm
Storage Store at -20°C

Computed Properties

XLogP3 10.6
Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 4
Rotatable Bond Count 20
Exact Mass 592.36986470 g/mol
Monoisotopic Mass 592.36986470 g/mol
Topological Polar Surface Area 72.7Ų
Heavy Atom Count 42
Formal Charge 0
Complexity 789
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 1
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

Patents

Publication NumberTitlePriority Date
EP-3568677-A1 Systems and methods for detection 2017-01-10
US-2019346368-A1 Systems and methods for detection 2017-01-10
US-11041806-B2 Systems and methods for detection 2017-01-10
US-2022026364-A1 Systems and methods for detection 2017-01-10
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