![{[Name]}](https://resource.bocsci.com/structure/92-71-7.gif?v=2025011501)
![{[Name]}](https://resource.bocsci.com/structure/15082-28-7.gif?v=2025011501)
![{[Name]}](https://resource.bocsci.com/structure/3071-70-3.gif?v=2025011501)
![{[Name]}](https://resource.bocsci.com/structure/846-63-9.gif?v=2025011501)
![{[Name]}](https://resource.bocsci.com/structure/19764-96-6.gif?v=2025011501)
![{[Name]}](https://resource.bocsci.com/structure/2083-09-2.gif?v=2025011501)
Inquiry Basket
Cy7-NHS ester | CAS 477908-53-5
| Catalog Number | A17-0083 |
| Category | Laser Dyes |
| Molecular Formula | C39H45N3O10S2 |
| Molecular Weight | 779.92 |
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
Cy7-NHS ester is a near IR dye.
Chemical Information
Application
| Synonyms | Cyanine 7, SE; Cy7-SE; Sulfo-Cyanine7 Succinimidyl Ester |
| IUPAC Name | (2Z)-2-[(2E,4E,6E)-7-[1-[6-(2,5-dioxopyrrolidin-1-yl)oxy-6-oxohexyl]-3,3-dimethyl-5-sulfoindol-1-ium-2-yl]hepta-2,4,6-trienylidene]-1-ethyl-3,3-dimethylindole-5-sulfonate |
| Canonical SMILES | CCN1C2=C(C=C(C=C2)S(=O)(=O)[O-])C(C1=CC=CC=CC=CC3=[N+](C4=C(C3(C)C)C=C(C=C4)S(=O)(=O)O)CCCCCC(=O)ON5C(=O)CCC5=O)(C)C |
| InChI | InChI=1S/C39H45N3O10S2/c1-6-40-31-20-18-27(53(46,47)48)25-29(31)38(2,3)33(40)15-11-8-7-9-12-16-34-39(4,5)30-26-28(54(49,50)51)19-21-32(30)41(34)24-14-10-13-17-37(45)52-42-35(43)22-23-36(42)44/h7-9,11-12,15-16,18-21,25-26H,6,10,13-14,17,22-24H2,1-5H3,(H-,4 |
| InChIKey | ROGODJHHEBREAB-UHFFFAOYSA-N |
| Appearance | Light Brown to Black Solid |
Cy7-NHS ester, a versatile fluorescent dye, finds applications in labeling proteins, peptides, and other biomolecules for a multitude of uses. Below are four key applications of Cy7-NHS ester:
Fluorescence Imaging: Widely utilized in fluorescence imaging, Cy7-NHS ester emits near-infrared light that penetrates deep into tissues with minimal background interference. Scientists leverage this dye to visualize intricate cellular structures, track labeled biomolecules, and monitor dynamic biological processes in real time. Particularly vital in in vivo imaging, where clear and detailed images are paramount for unraveling disease progression and assessing treatment efficacy.
Flow Cytometry: A favored choice for conjugation in flow cytometry, Cy7-NHS ester’s distinct emission spectrum enables multiparametric analysis, facilitating the simultaneous examination of numerous cell surface markers. This application is indispensable in immunology and related fields where precise identification and characterization of cell populations are essential for advancing research and understanding complex immune responses.
Western Blotting: In protein studies, Cy7-NHS ester plays a crucial role in enhancing the sensitivity of protein detection in Western blotting experiments. Its near-infrared fluorescence minimizes background noise, improving the signal-to-noise ratio for accurate quantification and visualization of protein bands. This capability is particularly valuable when analyzing proteins present in low abundance, enhancing the accuracy and reliability of experimental results.
In Vivo Tracking: Employed for tracking the biodistribution of biomolecules, cells, or nanoparticles within living organisms, Cy7-NHS ester enables researchers to monitor the movement and localization of these entities over time using specialized imaging techniques. This application is pivotal in preclinical research, providing insights into pharmacokinetics, cell migration, and therapeutic targeting, ultimately advancing our understanding of complex biological processes and aiding in the development of targeted therapies.
Recommended Services
Recommended Articles
- Hoechst Dyes: Definition, Structure, Mechanism and Applications
- Mastering the Spectrum: A Comprehensive Guide to Cy3 and Cy5 Dyes
- Fluorescent Probes: Definition, Structure, Types and Application
- Fluorescent Dyes: Definition, Mechanism, Types and Application
- Coumarin Dyes: Definition, Structure, Benefits, Synthesis and Uses
- BODIPY Dyes: Definition, Structure, Synthesis and Uses
- Cyanine Dyes: Definition, Structure, Types and Uses
- Fluorescein Dyes: Definition, Structure, Synthesis and Uses
- Rhodamine Dyes: Definition, Structure, Uses, Excitation and Emission
- Unlocking the Power of Fluorescence Imaging: A Comprehensive Guide
- Cell Imaging: Definitions, Systems, Protocols, Dyes, and Applications
- Lipid Staining: Definition, Principles, Methods, Dyes, and Uses
- Flow Cytometry: Definition, Principles, Protocols, Dyes, and Uses
- Nucleic Acid Staining: Definition, Principles, Dyes, Procedures, and Uses
- DNA Staining: Definition, Procedures, Benefits, Dyes and Uses
- Cell Staining: Definition, Principles, Protocols, Dyes, and Uses
- Ion Imaging: Definition, Principles, Benefits, Dyes, and Uses
- Fluorescent Labeling: Definition, Principles, Types and Applications
Recommended Products
Online Inquiry
