Coumarin 510

What We Offer

Coumarin 510

Coumarin 510 | 87349-92-6

Catalog Number A17-0117
Category Laser Dyes
Molecular Formula C20H18N2O2
Molecular Weight 318.376
Catalog Number Size Price Quantity
A17-0117 -- $--

Product Introduction

Coumarin 510 is a fluorescent dye widely used in biomedicine for labeling various biomolecules and tracking cellular activity. It is particularly useful in research involving cancer cells, as it allows for visualization and analysis of tumor growth and metastasis. Coumarin 510 has also been employed in drug delivery systems, enabling targeted therapy for ailments like cardiovascular diseases and neurodegenerative disorders.

Chemical Information

Synonyms 2,3,6,7-tetrahydro-10-(3-pyridinyl)-1H,5H,11H-[1]benzopyrano[6,7,8-ij]quinolizin-11-one
IUPAC Name 5-pyridin-3-yl-3-oxa-13-azatetracyclo[7.7.1.02,7.013,17]heptadeca-1,5,7,9(17)-tetraen-4-one
Canonical SMILES C1CC2=C3C(=C4C(=C2)C=C(C(=O)O4)C5=CN=CC=C5)CCCN3C1
InChI InChI=1S/C20H18N2O2/c23-20-17(14-4-1-7-21-12-14)11-15-10-13-5-2-8-22-9-3-6-16(18(13)22)19(15)24-20/h1,4,7,10-12H,2-3,5-6,8-9H2
InChI Key OEEAIIVRKIVRNX-UHFFFAOYSA-N
  • Application

Coumarin 510, a versatile fluorescent dye, finds a multitude of uses in scientific research and industrial applications. Here are four key applications of Coumarin 510:

Cell Imaging: Within the realm of cell biology, Coumarin 510 emerges as a prominent tool for fluorescence microscopy. Its radiant and enduring fluorescence empowers researchers to intricately label and vividly visualize cellular structures and processes. This dye proves especially valuable in illuminating the dynamic intricacies of intracellular components, such as organelles and the cytoskeleton, offering unprecedented clarity in exploring the inner workings of cells.

Flow Cytometry: In the domain of flow cytometry, Coumarin 510 takes center stage as a vital staining agent for characterizing and analyzing cells. By tagging specific cell surface markers with this luminescent dye, researchers can precisely identify and quantify diverse cell populations within a given sample. This technique plays a pivotal role in advancing fields such as immunology, cancer research, and diagnostic applications, amplifying our understanding of cellular behaviors and responses.

Biochemical Assays: Coumarin 510 assumes the role of a fluorescence probe in biochemical assays, facilitating the detection of enzyme activities and biochemical interactions. Incorporated into substrates that emit a fluorescent signal upon enzymatic cleavage, this dye enables efficient high-throughput screening of enzyme inhibitors or activators within drug discovery programs. Its versatility and sensitivity make it a key player in unraveling intricate biochemical processes.

Material Sciences: Within the expansive domain of material sciences, Coumarin 510 contributes to the development of fluorescent materials and sensors with remarkable functionality. Integrated into polymer matrices, this dye enables the creation of materials that exhibit responsive behaviors to environmental stimuli like pH or temperature changes. These innovative fluorescent materials find applications in diverse fields such as smart packaging, environmental monitoring, and biomedical diagnostics, showcasing the versatility and utility of Coumarin 510 in cutting-edge material innovations.

Computed Properties

XLogP3 3.4
Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 4
Rotatable Bond Count 1
Exact Mass 318.136827821 g/mol
Monoisotopic Mass 318.136827821 g/mol
Topological Polar Surface Area 42.4Ų
Heavy Atom Count 24
Formal Charge 0
Complexity 546
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

Patents

Publication NumberTitlePriority Date
US-2016202560-A1 Photo-alignment material and photo-alignment method 2013-08-14
US-2019086738-A1 Photo-alignment material and photo-alignment method 2013-08-14
US-10788715-B2 Photo-alignment material and photo-alignment method 2013-08-14
US-2010062375-A1 Method of preparing lithographic printing plate 2008-08-29
US-2010040978-A1 Photosensitive lithographic printing plate material 2007-01-10
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