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Coumarin 510 | CAS 87349-92-6
| Catalog Number | A17-0117 |
| Category | Laser Dyes |
| Molecular Formula | C20H18N2O2 |
| Molecular Weight | 318.376 |
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
Coumarin 510 is a fluorescent dye widely used in biomedicine for labeling various biomolecules and tracking cellular activity. It is particularly useful in research involving cancer cells, as it allows for visualization and analysis of tumor growth and metastasis. Coumarin 510 has also been employed in drug delivery systems, enabling targeted therapy for ailments like cardiovascular diseases and neurodegenerative disorders.
Chemical Information
Application
Computed Properties
Patents
| Synonyms | 2,3,6,7-tetrahydro-10-(3-pyridinyl)-1H,5H,11H-[1]benzopyrano[6,7,8-ij]quinolizin-11-one |
| IUPAC Name | 5-pyridin-3-yl-3-oxa-13-azatetracyclo[7.7.1.02,7.013,17]heptadeca-1,5,7,9(17)-tetraen-4-one |
| Canonical SMILES | C1CC2=C3C(=C4C(=C2)C=C(C(=O)O4)C5=CN=CC=C5)CCCN3C1 |
| InChI | InChI=1S/C20H18N2O2/c23-20-17(14-4-1-7-21-12-14)11-15-10-13-5-2-8-22-9-3-6-16(18(13)22)19(15)24-20/h1,4,7,10-12H,2-3,5-6,8-9H2 |
| InChIKey | OEEAIIVRKIVRNX-UHFFFAOYSA-N |
Coumarin 510, a versatile fluorescent dye, finds a multitude of uses in scientific research and industrial applications. Here are four key applications of Coumarin 510:
Cell Imaging: Within the realm of cell biology, Coumarin 510 emerges as a prominent tool for fluorescence microscopy. Its radiant and enduring fluorescence empowers researchers to intricately label and vividly visualize cellular structures and processes. This dye proves especially valuable in illuminating the dynamic intricacies of intracellular components, such as organelles and the cytoskeleton, offering unprecedented clarity in exploring the inner workings of cells.
Flow Cytometry: In the domain of flow cytometry, Coumarin 510 takes center stage as a vital staining agent for characterizing and analyzing cells. By tagging specific cell surface markers with this luminescent dye, researchers can precisely identify and quantify diverse cell populations within a given sample. This technique plays a pivotal role in advancing fields such as immunology, cancer research, and diagnostic applications, amplifying our understanding of cellular behaviors and responses.
Biochemical Assays: Coumarin 510 assumes the role of a fluorescence probe in biochemical assays, facilitating the detection of enzyme activities and biochemical interactions. Incorporated into substrates that emit a fluorescent signal upon enzymatic cleavage, this dye enables efficient high-throughput screening of enzyme inhibitors or activators within drug discovery programs. Its versatility and sensitivity make it a key player in unraveling intricate biochemical processes.
Material Sciences: Within the expansive domain of material sciences, Coumarin 510 contributes to the development of fluorescent materials and sensors with remarkable functionality. Integrated into polymer matrices, this dye enables the creation of materials that exhibit responsive behaviors to environmental stimuli like pH or temperature changes. These innovative fluorescent materials find applications in diverse fields such as smart packaging, environmental monitoring, and biomedical diagnostics, showcasing the versatility and utility of Coumarin 510 in cutting-edge material innovations.
| XLogP3 | 3.4 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 1 |
| Exact Mass | 318.136827821 g/mol |
| Monoisotopic Mass | 318.136827821 g/mol |
| Topological Polar Surface Area | 42.4Ų |
| Heavy Atom Count | 24 |
| Formal Charge | 0 |
| Complexity | 546 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
| Publication Number | Title | Priority Date |
|---|---|---|
| US-2016202560-A1 | Photo-alignment material and photo-alignment method | 2013-08-14 |
| US-2019086738-A1 | Photo-alignment material and photo-alignment method | 2013-08-14 |
| US-10788715-B2 | Photo-alignment material and photo-alignment method | 2013-08-14 |
| US-2010062375-A1 | Method of preparing lithographic printing plate | 2008-08-29 |
| US-2010040978-A1 | Photosensitive lithographic printing plate material | 2007-01-10 |
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