Coumarin 478 | CAS 41175-45-5

Catalog Number	A17-0074
Category	Laser Dyes
Molecular Formula	C18H19NO2
Molecular Weight	281.35

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Product Introduction

Blue-emitting fluorophore for spectroscopy and photonics. Known for high purity and excellent quantum efficiency.

Chemical Information
Application

Synonyms	2,3,6,7,10,11-hexahydro-1H,5H-cyclopenta[3,4][1]benzopyrano[6,7,8-ij]quinolizin-12(9H)-one; Coumarin 106
Canonical SMILES	C1CC2=C(C1)C(=O)OC3=C4CCCN5C4=C(CCC5)C=C23
InChI	InChI=1S/C18H19NO2/c20-18-13-6-1-5-12(13)15-10-11-4-2-8-19-9-3-7-14(16(11)19)17(15)21-18/h10H,1-9H2
InChIKey	LLSRPENMALNOFW-UHFFFAOYSA-N

Coumarin 478, a fluorescent chemical compound widely utilized in scientific research and industrial settings, presents a myriad of applications. Here are four key applications:

Fluorescence Microscopy: At the forefront of scientific exploration, Coumarin 478 serves as a pivotal fluorescent dye in microscopy, enhancing the visualization of biological samples. Its robust fluorescence properties enable researchers to elucidate cellular and subcellular structures with exceptional clarity, facilitating in-depth studies of cell biology, histology, and various biomedical disciplines.

Fluorescent Probes: Delving into the realm of molecular detection, Coumarin 478 emerges as a key component in developing fluorescent probes for precise biomolecule tracking. When coupled with targeting molecules like antibodies or nucleic acids, it becomes a potent tool for monitoring the presence and distribution of proteins, DNA, and other targets in intricate biological systems. This application stands as a cornerstone in molecular and diagnostic assays, bolstering research endeavors.

Environmental Monitoring: In the field of environmental science, Coumarin 478 takes on a crucial role as a tracer for analyzing water and pollutant movement. Its distinct fluorescence characteristics simplify detection and quantification in environmental samples, aiding in the surveillance of contaminant dispersal and the comprehension of ecological impacts. This application offers invaluable insights into environmental dynamics and sustainability efforts.

Pharmaceutical Formulation: Within pharmaceutical research, Coumarin 478 emerges as a valuable model compound for investigating drug delivery mechanisms. Its fluorescence acts as a beacon for monitoring the distribution and release patterns of drug formulations both in vitro and in vivo. This surveillance capability contributes to the refinement of drug delivery systems.