Coumarin 466 | CAS 20571-42-0

Catalog Number	A17-0043
Category	Laser Dyes
Molecular Formula	C13H15NO2
Molecular Weight	217.27

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Product Introduction

High-stability fluorescent dye producing strong blue emission. Ideal for time-resolved fluorescence and environmental sensing.

Chemical Information
Application

Synonyms	7-(diethylamino)-2H-1-benzopyran-2-one; LD 466; 7-(Diethylamino) coumarin
Canonical SMILES	CCN(CC)C1=CC2=C(C=C1)C=CC(=O)O2
InChI	InChI=1S/C13H15NO2/c1-3-14(4-2)11-7-5-10-6-8-13(15)16-12(10)9-11/h5-9H,3-4H2,1-2H3
InChIKey	QXAMGWKESXGGNV-UHFFFAOYSA-N

Coumarin 466, a versatile fluorescent molecule, finds diverse applications across various bioscience domains. Here are four key applications of Coumarin 466:

Molecular Imaging: Renowned for its robust fluorescent properties, Coumarin 466 plays a pivotal role in molecular imaging, enabling the visualization of biomolecules like proteins and nucleic acids. This facilitates the observation of cellular processes in real-time, a crucial aspect in live-cell imaging for monitoring dynamic biological activities.

Fluorescence Microscopy: Within fluorescence microscopy, Coumarin 466 stands out as an exceptional fluorescent dye that enhances the staining of cellular components with its bright fluorescence and exceptional photostability. Researchers leverage its capabilities to distinguish between various cellular structures and to trace the movement of molecules within cells, offering unprecedented insights into cellular dynamics.

Biosensors: Coumarin 466 contributes significantly to biosensor development, aiding in the detection of specific biological molecules. Through the conjugation of Coumarin 466 with recognition elements like antibodies or enzymes, biosensors can provide fluorescence signals indicating the presence and concentration of target molecules. These advanced biosensors incorporating Coumarin 466 are instrumental in diagnostics and environmental monitoring efforts.

Drug Delivery Research: In the realm of drug delivery studies, Coumarin 466 emerges as a crucial tool for monitoring the distribution and release of drug carriers within biological systems. By tagging drug delivery vehicles with Coumarin 466, researchers can track their localization and degradation in real-time through fluorescence, offering valuable insights for optimizing delivery strategies and comprehending the pharmacokinetics of therapeutic compounds.