C12 NBD Phytoceramide
Catalog Number | A16-0045 |
Category | Lipid Fluorescent Probes |
Molecular Formula | C36H63N5O7 |
Molecular Weight | 677.9 |
Catalog Number | Size | Price | Quantity |
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A16-0045 | -- | $-- |
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Product Introduction
C12 NBD phytoceramide is a phytosphingosine derivative that is tagged with a fluorescent group C12 nitrobenzoxadiazole (C12 NBD). C12 NBD phytosphingosine has been used to study the metabolism of ceramides using microsomes expressing the S. cerevisiae diacylglycerol Lro1p.
Chemical Information |
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Synonyms | C12 NBD Phytosphingosine; N-dodecanoyl-NBD Phytosphingosine; 12-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)-N-((2R,3R,4R)-1,3,4-trihydroxyoctadecan-2-yl)dodecanamide |
Purity | ≥98% |
IUPAC Name | 12-[(4-nitro-2,1,3-benzoxadiazol-6-yl)amino]-N-[(2R,3R,4R)-1,3,4-trihydroxyoctadecan-2-yl]dodecanamide |
Canonical SMILES | CCCCCCCCCCCCCCC(C(C(CO)NC(=O)CCCCCCCCCCCNC1=CC2=NON=C2C(=C1)[N+](=O)[O-])O)O |
InChI | InChI=1S/C36H63N5O7/c1-2-3-4-5-6-7-8-9-11-14-17-20-23-33(43)36(45)31(28-42)38-34(44)24-21-18-15-12-10-13-16-19-22-25-37-29-26-30-35(40-48-39-30)32(27-29)41(46)47/h26-27,31,33,36-37,42-43,45H,2-25,28H2,1H3,(H,38,44)/t31-,33-,36-/m1/s1 |
InChI Key | UDGQTVVIGGXNEN-YCOLFDFNSA-N |
Appearance | Solid Powder |
- Product Specification
- Application
Storage | Store at -20°C |
C12 NBD Phytoceramide, a fluorescently labeled sphingolipid analog, finds diverse applications in research and analytical settings. Explore its versatility through these four key applications:
Cellular Imaging: Delve into the intricate realm of sphingolipid metabolism and cell membrane dynamics using C12 NBD Phytoceramide in fluorescence microscopy studies. This potent tool allows researchers to visualize the intricate distribution and trafficking patterns of ceramides within cellular structures. Gain profound insights into cellular processes such as apoptosis, autophagy, and lipid raft formation through this cutting-edge application.
Lipidomics Research: Unravel the mysteries of lipid metabolism pathways with C12 NBD Phytoceramide as your guide in the realm of lipidomics. This dynamic tool can be seamlessly integrated into cellular membranes, offering a window into the intricate dance of ceramide metabolism and its implications on cellular functions. Broaden your understanding of ceramides’ biological significance and their role in various disease states through this invaluable research tool.
Drug Delivery Studies: Embark on a journey of discovery into drug delivery mechanisms and lipid-based systems using C12 NBD Phytoceramide as a beacon of fluorescence. Track lipid nanoparticles and liposomes in cellular environments with ease, thanks to the luminous properties of this versatile compound. Evaluate the efficacy and stability of drug carriers with precision and finesse through this cutting-edge application.
Computed Properties | |
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XLogP3 | 9.9 |
Hydrogen Bond Donor Count | 5 |
Hydrogen Bond Acceptor Count | 10 |
Rotatable Bond Count | 30 |
Exact Mass | 677.47274937 g/mol |
Monoisotopic Mass | 677.47274937 g/mol |
Topological Polar Surface Area | 187Ų |
Heavy Atom Count | 48 |
Formal Charge | 0 |
Complexity | 820 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 3 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
Applications of Fluorescent Probes & Dyes
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