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Ac-LETD-AFC | 210345-02-1
| Catelog Number | A18-0010 |
| Category | Fluorescent Enzyme Substrates |
| Molecular Formula | C31H38F3N5O12 |
| Molecular Weight | 729.7 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| A18-0010 | -- | $-- |
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Product Introduction
Ac-LETD-AFC is a fluorogenic substrate for caspase-8. Caspase activity can be quantified by fluorescent detection of free AFC (7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.
Chemical Information |
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| Synonyms | N-Acetyl-Leu-Glu-Thr-Asp-7-amino-4-Trifluoromethylcoumarin; N-acetyl-L-leucyl-L-α-glutamyl-L-threonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine |
| Purity | ≥95% |
| Canonical SMILES | CC(C)CC(C(=O)NC(CCC(=O)O)C(=O)NC(C(C)O)C(=O)NC(CC(=O)O)C(=O)NC1=CC2=C(C=C1)C(=CC(=O)O2)C(F)(F)F)NC(=O)C |
| InChI | InChI=1S/C31H38F3N5O12/c1-13(2)9-20(35-15(4)41)29(49)37-19(7-8-23(42)43)27(47)39-26(14(3)40)30(50)38-21(12-24(44)45)28(48)36-16-5-6-17-18(31(32,33)34)11-25(46)51-22(17)10-16/h5-6,10-11,13-14,19-21,26,40H,7-9,12H2,1-4H3,(H,35,41)(H,36,48)(H,37,49)(H,38,50)(H,39,47)(H,42,43)(H,44,45)/t14-,19+,20+,21+,26+/m1/s1 |
| InChI Key | KTZOWCXXAYFIFT-XSSXFGQWSA-N |
| Appearance | Solid Powder |
Product Specification |
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| Excitation | 400 nm |
| Emission | 505 nm |
| Storage | Store at -20°C |
Applications of Fluorescent Probes & Dyes
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