Inquiry Basket
6-Carboxyfluorescein | 3301-79-9
| Catelog Number | A16-0033 |
| Category | Fluorescein FAM |
| Molecular Formula | C21H12O7 |
| Molecular Weight | 376.32 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| A16-0033 | 1 g | $279 |
- Worldwide Delivery
- Quality Assurance
- 24/7 Customer Service
Product Introduction
6-Carboxyfluorescein (6-FAM) is a fluorescent dye used for labeling nucleotides and nucleic acids.
Chemical Information |
|
|---|---|
| Synonyms | 6-FAM; (3,6,9-Trihydroxyxanthen-9-yl)terephthalic Acid; 3',6'-dihydroxy-3-oxo-spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylic acid |
| Purity | ≥95% by HPLC |
| IUPAC Name | 3',6'-dihydroxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-carboxylic acid |
| Canonical SMILES | C1=CC2=C(C=C1C(=O)O)C3(C4=C(C=C(C=C4)O)OC5=C3C=CC(=C5)O)OC2=O |
| InChI | InChI=1S/C21H12O7/c22-11-2-5-14-17(8-11)27-18-9-12(23)3-6-15(18)21(14)16-7-10(19(24)25)1-4-13(16)20(26)28-21/h1-9,22-23H,(H,24,25) |
| InChI Key | BZTDTCNHAFUJOG-UHFFFAOYSA-N |
| Solubility | Soluble in DMF (Slightly), DMSO (Slightly) |
| Density | 1.73±0.1 g/cm3 (Predicted) |
| Appearance | Yellow to Orange Solid |
| Boiling Point | 736.4±60.0°C (Predicted) |
| Melting Point | >300°C |
Product Specification |
|
|---|---|
| Excitation | 492 nm |
| Emission | 518 nm |
| Storage | Store at -20°C |
| Signal | Warning |
| GHS Hazard Statements | H315 (95.24%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] |
| Precautionary Statement Codes | P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (The corresponding statement to each P-code can be found at the GHS Classification page.) |
Computed Properties | |
|---|---|
| XLogP3 | 2.9 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 1 |
| Exact Mass | 376.05830272 g/mol |
| Monoisotopic Mass | 376.05830272 g/mol |
| Topological Polar Surface Area | 113Ų |
| Heavy Atom Count | 28 |
| Formal Charge | 0 |
| Complexity | 637 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 29030288 | 2018-02-01 | In vitro characterization of zebrafish (Danio rerio) organic anion transporters Oat2a-e | Toxicology in vitro : an international journal published in association with BIBRA |
| 28597291 | 2017-12-01 | Multiple drug transporters mediate the placental transport of sulpiride | Archives of toxicology |
| 28629854 | 2017-10-01 | Inhibition of organic anion transporter (OAT) activity by cigarette smoke condensate | Toxicology in vitro : an international journal published in association with BIBRA |
| 23082315 | 2012-12-07 | A ligation-triggered highly sensitive fluorescent assay of adenosine triphosphate based on graphene oxide | The Analyst |
| 22895529 | 2012-11-21 | Solute transport on the sub 100 ms scale across the lipid bilayer membrane of individual proteoliposomes | Lab on a chip |
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114894767-A | Fluorescence calibration piece for PCR instrument and method of making the same | 2022-07-06 |
| CN-115029128-A | A kind of autophagy monitoring probe and preparation method thereof | 2022-07-05 |
| CN-115029460-A | A real-time visual detection method for Haemophilus parasuis | 2022-07-05 |
| CN-114854886-A | A real-time fluorescent PCR detection method and application of Edwardsiella lentus | 2022-06-30 |
| CN-115094122-A | A kit and application for visual detection of R. anatipestifer based on RPA-CRISPR-Cas12a | 2022-06-28 |
Applications of Fluorescent Probes & Dyes
Get More Product Details?
