![{[Name]}](https://resource.bocsci.com/structure/83907-41-9.gif?v=2025011501)
![{[Name]}](https://resource.bocsci.com/structure/1228181-72-3.gif?v=2025011501)
![{[Name]}](https://resource.bocsci.com/structure/80528-89-8.gif?v=2025011501)
![{[Name]}](https://resource.bocsci.com/structure/96315-18-3.gif?v=2025011501)
![{[Name]}](https://resource.bocsci.com/structure/1299464-59-7.gif?v=2025011501)
![{[Name]}](https://resource.bocsci.com/structure/98907-26-7.gif?v=2025011501)
Inquiry Basket
Zinpyr-1 | CAS 288574-78-7
| Catalog Number | A14-0014 |
| Category | Calcium, Chloride and Other indicators |
| Molecular Formula | C46H36Cl2N6O5 |
| Molecular Weight | 823.7 |
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
Zinpyr-1 is a cell-permeable fluorescent probe for Zn2+.
Chemical Information
Product Specification
Application
| Synonyms | ZP-1; 4',5'-bis[[bis(2-pyridinylmethyl)amino]methyl]-2',7'-dichloro-3',6'-dihydroxy-spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one |
| Purity | ≥90% |
| Canonical SMILES | C1=CC=C(C(=C1)C2=C3C=C(C(=O)C(=C3OC4=C(C(=C(C=C24)Cl)[O-])C[NH+](CC5=CC=CC=N5)CC6=CC=CC=N6)C[NH+](CC7=CC=CC=N7)CC8=CC=CC=N8)Cl)C(=O)[O-] |
| InChI | InChI=1S/C46H36Cl2N6O5/c47-39-21-35-41(33-15-1-2-16-34(33)46(57)58)36-22-40(48)43(56)38(28-54(25-31-13-5-9-19-51-31)26-32-14-6-10-20-52-32)45(36)59-44(35)37(42(39)55)27-53(23-29-11-3-7-17-49-29)24-30-12-4-8-18-50-30/h1-22,55H,23-28H2,(H,57,58) |
| InChIKey | NKEYRLVORYSIBB-UHFFFAOYSA-N |
| Appearance | Pale Red to Light Red Solid |
| Excitation | 515-507 nm |
| Emission | 513-558 nm |
| Storage | Store at -20°C |
Zinpyr-1 is a fluorescent chemical compound known for its ability to selectively bind to zinc ions (Zn²⁺) in biological systems. Specifically designed for bioimaging applications, Zinpyr-1 exhibits high specificity due to its complex structure composed of a fluorescent moiety conjugated to a zinc chelating ligand. This unique structural configuration not only promotes selectivity for zinc ions but also facilitates changes in fluorescence intensity upon binding, making it a powerful tool for tracking zinc dynamics in live cells and tissues. Developed to overcome the limitations of traditional zinc detection methods, Zinpyr-1’s design allows for real-time, non-invasive imaging, thereby providing vital insights into the roles of zinc in various biological processes.
One of the key applications of Zinpyr-1 is its use in neuroscience research. Zinc ions play a critical role in neurotransmission and neuroplasticity within the brain. By using Zinpyr-1, researchers can visualize and quantify zinc in neurons, helping to elucidate the role of this metal ion in synaptic transmission and in the modulation of neuronal signaling pathways. This is particularly important in studies related to memory, learning, and neurodegenerative diseases, where dysregulation of zinc homeostasis has been implicated.
Another significant application of Zinpyr-1 is in cancer research. Zinc’s involvement in cell division and apoptosis is a focal point of investigation, as altered zinc levels can contribute to tumor progression and metastasis. Zinpyr-1 enables scientists to monitor zinc flux within cancer cells, providing insights that may lead to the development of novel therapeutic strategies targeting zinc-dependent pathways. By enhancing the understanding of zinc’s role in cell growth and death, Zinpyr-1 aids in identifying potential biomarkers for cancer diagnosis and prognosis.
In addition to its biomedical applications, Zinpyr-1 has a crucial role in environmental science, particularly in monitoring zinc pollution. Zinc is a common environmental contaminant due to industrial activities, and its excessive levels can be detrimental to ecosystems. Zinpyr-1’s sensitivity and selectivity make it ideal for detecting trace amounts of zinc in various environmental samples, such as water and soil, facilitating efficient monitoring and assessment of pollution levels. This application is vital for implementing regulatory measures and for ensuring ecological safety.
Lastly, Zinpyr-1 is applied in nutritional science to study zinc metabolism and its kinetics within the human body. Given zinc’s importance in immune function, enzyme activity, and DNA synthesis, understanding how the body absorbs and distributes zinc is essential. Zinpyr-1 allows researchers to trace zinc uptake in vivo, providing data that can inform dietary recommendations and address deficiencies effectively. It is instrumental in exploring how different physiological conditions and dietary regimes impact zinc bioavailability and utilization.
Recommended Services
Recommended Articles
- Hoechst Dyes: Definition, Structure, Mechanism and Applications
- Mastering the Spectrum: A Comprehensive Guide to Cy3 and Cy5 Dyes
- Fluorescent Probes: Definition, Structure, Types and Application
- Fluorescent Dyes: Definition, Mechanism, Types and Application
- Coumarin Dyes: Definition, Structure, Benefits, Synthesis and Uses
- BODIPY Dyes: Definition, Structure, Synthesis and Uses
- Cyanine Dyes: Definition, Structure, Types and Uses
- Fluorescein Dyes: Definition, Structure, Synthesis and Uses
- Rhodamine Dyes: Definition, Structure, Uses, Excitation and Emission
- Unlocking the Power of Fluorescence Imaging: A Comprehensive Guide
- Cell Imaging: Definitions, Systems, Protocols, Dyes, and Applications
- Lipid Staining: Definition, Principles, Methods, Dyes, and Uses
- Flow Cytometry: Definition, Principles, Protocols, Dyes, and Uses
- Nucleic Acid Staining: Definition, Principles, Dyes, Procedures, and Uses
- DNA Staining: Definition, Procedures, Benefits, Dyes and Uses
- Cell Staining: Definition, Principles, Protocols, Dyes, and Uses
- Ion Imaging: Definition, Principles, Benefits, Dyes, and Uses
- Fluorescent Labeling: Definition, Principles, Types and Applications
Recommended Products
Online Inquiry
