Pyrromethene 556 | CAS 121461-69-6

Catalog Number	F01-0153
Category	BODIPY
Molecular Formula	C14H15BF2N2O6S2Na2
Molecular Weight	466.188

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Product Introduction

Pyrromethene 556 is a green-fluorescent polar tracer dye. It is used for investigations of membrane fusion, lysis, and gap-junctional communication and to detect volume changes in cells or liposomes.

Chemical Information
Product Specification
Application

Synonyms	[[(3,5-Dimethyl-4-sulfo-1H-pyrrol-2-yl)(3,5-dimethyl-4-sulfo-2H-pyrrol-2-ylidene)methyl]methane](difluoroborane) Disodium Salt; PMPDS-BF2; EverFluor 492/515 Disulfonate
Canonical SMILES	[B-]1(N2C(=C(C(=C2C(=C3[N+]1=C(C(=C3C)S(=O)(=O)[O-])C)C)C)S(=O)(=O)[O-])C)(F)F.[Na+].[Na+]
InChI	InChI=1S/C14H17BF2N2O6S2.2Na/c1-6-11-7(2)13(26(20,21)22)9(4)18(11)15(16,17)19-10(5)14(27(23,24)25)8(3)12(6)19;;/h1-5H3,(H,20,21,22)(H,23,24,25);;/q;2*+1/p-2
InChIKey	FBAASMARNAYERO-UHFFFAOYSA-L

Excitation	494
Emission	517

Pyrromethene 556 is a fluorescent dye with unique optical properties that make it useful in various scientific and industrial applications. Here are some key applications of Pyrromethene 556.

Laser Systems: Pyrromethene 556 is widely used in dye lasers due to its high fluorescence efficiency and tunable emission wavelength. It serves as a gain medium in laser systems, allowing for the generation of laser light across a wide spectrum. This application is critical in spectroscopy, medical diagnostics, and laser-based industrial processes.

Fluorescence Microscopy: In biological research, Pyrromethene 556 is used as a fluorescent marker for imaging purposes. Its strong fluorescence emission allows for the visualization and tracking of cellular components and molecular interactions. This application aids in elucidating complex biological processes and improving our understanding of cellular dynamics.

Optical Sensors: Pyrromethene 556 can be utilized in the development of optical sensors for detecting environmental changes. Its fluorescence changes in response to different chemical or physical stimuli, making it highly sensitive in sensor applications. This is particularly valuable in creating devices for monitoring environmental pollutants or changes in biochemical conditions.

Photodynamic Therapy: Pyrromethene 556 shows potential in photodynamic therapy (PDT), a treatment method for certain types of cancer and infections. When activated by light, it generates reactive oxygen species that can target and kill cancerous or pathogen-infected cells. This application offers a promising alternative or complement to traditional therapies, focusing on targeted treatment with minimal side effects.