meso-CH2Br-BODIPY | CAS 216434-81-0

Catalog Number	F01-0064
Category	BODIPY
Molecular Formula	C14H16BBrF2N2
Molecular Weight	341.01

Catalog Number	Size	Price	Quantity
F01-0064	10 mg	$199

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Product Introduction

meso-CH₂Br-BODIPY is a reactive bromomethyl BODIPY dye for custom probe synthesis and bioconjugation. It offers strong fluorescence and excellent chemical stability.

Chemical Information
Product Specification
Application

Synonyms	BODIPY 493/503 Methyl Bromide; 8-Bromomethyl-4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-S-indacene
Purity	95%
IUPAC Name	8-(bromomethyl)-2,2-difluoro-4,6,10,12-tetramethyl-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-1(12),4,6,8,10-pentaene
Canonical SMILES	[B-]1(N2C(=CC(=C2C(=C3[N+]1=C(C=C3C)C)CBr)C)C)(F)F
InChI	InChI=1S/C14H16BBrF2N2/c1-8-5-10(3)19-13(8)12(7-16)14-9(2)6-11(4)20(14)15(19,17)18/h5-6H,7H2,1-4H3
InChIKey	JLSHPOSUMKVMAP-UHFFFAOYSA-N

Storage

Store at -20°C

meso-CH2Br-BODIPY, a versatile fluorescent dye molecule, finds extensive use in bioimaging and molecular detection. Here are four key applications of meso-CH2Br-BODIPY:

Fluorescence Imaging: meso-CH2Br-BODIPY shines as a beacon in fluorescence microscopy, where it is employed to label and visualize biomolecules and cellular structures. Its intense fluorescence and robust photostability render it an optimal selection for achieving high-resolution imaging capabilities. Researchers leverage this tool to monitor the dynamic processes unfolding within live cells, granting a real-time glimpse into cellular activities.

Flow Cytometry: A stalwart in flow cytometry, this compound acts as a potent fluorescent marker, facilitating the analysis of particles' physical and chemical attributes within a fluid sample. By conjugating meso-CH2Br-BODIPY with antibodies or ligands, researchers can accurately quantify and sort specific cell populations based on their unique fluorescence signatures. This application holds particular significance in the realms of immunology, cancer biology, and clinical diagnostics, enabling precise identification and characterization of cell populations.

Fluorescent Probes: meso-CH2Br-BODIPY serves as the cornerstone for designing a myriad of fluorescent probes tailored for detecting enzymatic activities and bioanalytes. These probes exhibit distinct fluorescence alterations upon interaction with specific targets, enabling highly sensitive detection capabilities. Such applications are instrumental in biochemical assays and high-throughput screening processes for drug discovery, providing researchers with invaluable insights into molecular interactions and pathways.

Biosensor Development: Engaging in the creation of optical biosensors, meso-CH2Br-BODIPY plays a pivotal role in detecting environmental pollutants, pathogens, and other analytes. Its adaptable fluorescence properties render it an ideal candidate for developing responsive sensors that generate measurable signals in the presence of target substances. This application enhances our ability to monitor and respond to environmental and health-related concerns, fostering advancements in biosensing technologies for improved public health and safety measures.