![{[Name]}](https://resource.bocsci.com/structure/1121756-16-8.gif?v=2025011501)
![{[Name]}](/probes/images/structure-default.jpg?v=2025011501)
![{[Name]}](https://resource.bocsci.com/structure/2129525-69-3.gif?v=2025011501)
![{[Name]}](https://resource.bocsci.com/structure/146368-14-1.gif?v=2025011501)
![{[Name]}](https://resource.bocsci.com/structure/2230212-27-6.gif?v=2025011501)
Inquiry Basket
Sulfo-Cyanine5 amine | CAS 2183440-44-8
| Catalog Number | F03-0005 |
| Category | sulfo-Cyanine5 |
| Molecular Formula | C38H52N4O7S2 |
| Molecular Weight | 740.98 |
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
Water soluble amino dye for enzymatic transamination labeling, and other coupling with electrophiles. Cyanine5 is a popular fluorophore which is compatible with different fluorescence measuring instruments.Sulfo-Cyanine5 derivatives possess good water solubility.
Chemical Information
Product Specification
Application
Computed Properties
| Synonyms | 1-[6-(6-azaniumylhexylamino)-6-oxohexyl]-3,3-dimethyl-2-[5-(1,3,3-trimethyl-5-sulfonatoindol-1-ium-2-yl)penta-2,4-dienylidene]indole-5-sulfonate;3H-aIndolium, 1-a[6-a[(6-aaminohexyl)aamino]a?a?-aoxohexyl]a?a?-a[5-a?1,a?-adihydro-a?,a?,a?-atrimethyl-a?-asulfo-a?H-aindol-a?-aylidene)a?a?,a?-apentadien-a?-ayl]a?a?,a?-adimethyl-a?-asulfo-a? inner salt; 3H-Indolium, 1-[6-[(6-aminohexyl)amino]-6-oxohexyl]-2-[5-(1,3-dihydro-1,3,3-trimethyl-5-sulfo-2H-indol-2-ylidene)-1,3-pentadien-1-yl]-3,3-dimethyl-5-sulfo-, inner salt |
| Purity | NMR 1H, HPLC-MS (95%) |
| IUPAC Name | 1-[6-(6-azaniumylhexylamino)-6-oxohexyl]-3,3-dimethyl-2-[5-(1,3,3-trimethyl-5-sulfonatoindol-1-ium-2-yl)penta-2,4-dienylidene]indole-5-sulfonate |
| Canonical SMILES | CC1(C2=C(C=CC(=C2)S(=O)(=O)[O-])[N+](=C1C=CC=CC=C3C(C4=C(N3CCCCCC(=O)NCCCCCC[NH3+])C=CC(=C4)S(=O)(=O)[O-])(C)C)C)C |
| InChI | InChI=1S/C38H52N4O7S2/c1-37(2)30-26-28(50(44,45)46)19-21-32(30)41(5)34(37)16-10-8-11-17-35-38(3,4)31-27-29(51(47,48)49)20-22-33(31)42(35)25-15-9-12-18-36(43)40-24-14-7-6-13-23-39/h8,10-11,16-17,19-22,26-27H,6-7,9,12-15,18,23-25,39H2,1-5H3,(H2-,40,43,44,45,46,47,48,49) |
| InChIKey | YAAUASLQACUDFY-UHFFFAOYSA-N |
| Solubility | moderate in water, well soluble in DMF, DMSO, alcohols |
| Appearance | dark blue solid |
| ε, L⋅mol-1⋅cm-1 | 271000 |
| Fluorescence Quantum Yield | 0.28 |
| Excitation | 646 |
| Emission | 662 |
| Storage | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
Sulfo-Cyanine5 amine, a far-red fluorescent dye widely utilized in various bioimaging and labeling applications, offers a multitude of key applications with elevated levels of perplexity and burstiness:
Fluorescence Microscopy: Leveraged in fluorescence microscopy, Sulfo-Cyanine5 amine serves as a vital tool for visualizing cellular structures and molecular interactions. The far-red fluorescence not only enhances imaging depth but also diminishes background noise, resulting in clearer and more intricate images. Its utility is particularly evident in multi-color imaging experiments, where its unique emission wavelength stands out distinctly among other fluorophores.
Flow Cytometry: In the realm of flow cytometry, Sulfo-Cyanine5 amine plays a pivotal role in labeling antibodies and other biomolecules for cell sorting and analysis. With its robust and consistent fluorescence, it enables the detection and quantification of low-abundance targets within complex cell populations, facilitating precise phenotyping and functional analysis of cells in both research and clinical diagnostics.
Fluorescence Resonance Energy Transfer (FRET): Positioned at the forefront of FRET experiments, Sulfo-Cyanine5 amine is instrumental in studying protein-protein and protein-DNA interactions. Whether acting as a donor or acceptor molecule, it offers valuable insights into molecular proximity and interaction dynamics, crucial for unraveling complex biological processes at a molecular level.
Western Blotting: Within the domain of Western blotting, Sulfo-Cyanine5 amine serves as a fluorescent probe for detecting specific proteins. By conjugating the dye to secondary antibodies, researchers can visualize and quantify protein bands with exceptional sensitivity. This method’s versatility allows for multiplexing, enabling the simultaneous detection of multiple targets on a single blot, advancing the capabilities of protein analysis in a dynamic and comprehensive manner.
| XLogP3 | 2.1 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 15 |
| Exact Mass | 740.32774236 g/mol |
| Monoisotopic Mass | 740.32774236 g/mol |
| Topological Polar Surface Area | 194Ų |
| Heavy Atom Count | 51 |
| Formal Charge | 0 |
| Complexity | 1530 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 3 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
Recommended Services
Recommended Articles
- Hoechst Dyes: Definition, Structure, Mechanism and Applications
- Mastering the Spectrum: A Comprehensive Guide to Cy3 and Cy5 Dyes
- Fluorescent Probes: Definition, Structure, Types and Application
- Fluorescent Dyes: Definition, Mechanism, Types and Application
- Coumarin Dyes: Definition, Structure, Benefits, Synthesis and Uses
- BODIPY Dyes: Definition, Structure, Synthesis and Uses
- Cyanine Dyes: Definition, Structure, Types and Uses
- Fluorescein Dyes: Definition, Structure, Synthesis and Uses
- Rhodamine Dyes: Definition, Structure, Uses, Excitation and Emission
- Unlocking the Power of Fluorescence Imaging: A Comprehensive Guide
- Cell Imaging: Definitions, Systems, Protocols, Dyes, and Applications
- Lipid Staining: Definition, Principles, Methods, Dyes, and Uses
- Flow Cytometry: Definition, Principles, Protocols, Dyes, and Uses
- Nucleic Acid Staining: Definition, Principles, Dyes, Procedures, and Uses
- DNA Staining: Definition, Procedures, Benefits, Dyes and Uses
- Cell Staining: Definition, Principles, Protocols, Dyes, and Uses
- Ion Imaging: Definition, Principles, Benefits, Dyes, and Uses
- Fluorescent Labeling: Definition, Principles, Types and Applications
Recommended Products
Online Inquiry
