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Product Introduction
Controlled pore glass solid supports are used for the synthesis of 3'-labeled oligonucleotides. This solid support is intended for the synthesis of oligonucleotides bearing fluorescein (FAM) fluorescent dye on 3'-terminus of oligonucleotide. It contains pure 6-isomer of fluorescein. The structure of the reagent is based on chiral, enantiomerically pure scaffold of hydroxyprolinol. The solid support ensures optimal yield of oligonucleotides up to 60mer. For longer oligos, CPG 1000 should be used. The reagent is compatible with standard ammonia cleavage and deblocking conditions.
Chemical Information
Product Specification
| Appearance | off-white beads |
| ε, L⋅mol-1⋅cm-1 | 65±15 |
| Fluorescence Quantum Yield | ammonia, 2 h at room temperature |
| Excitation | 500 |
| Emission | standard coupling, identical to normal nucleobases |
| Storage | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
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