ATTO 610 maleimide
Catelog Number | F10-0131 |
Category | ATTO |
Molecular Formula | C31H37ClN4O7 |
Molecular Weight | 613.10 |
Catalog Number | Size | Price | Quantity |
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F10-0131 | -- | $-- |
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Chemical Information |
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Synonyms | ATTO 610-4; atto610-maleimide; Atto 610 maleimide, BioReagent, suitable for fluorescence, >=90% (coupling to thiols); 4-[9-(dimethylamino)-11,11-dimethyl-3,4-dihydro-2H-naphtho[2,3-g]quinolin-1-ium-1-yl]-N-[2-(2,5-dioxopyrrol-1-yl)ethyl]butanamide;perchlorate; 9-(dimethylamino)-1-(4-{[2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl]amino}-4-oxobutyl)-11,11-dimethyl-2,3,4,11-tetrahydronaphtho[2,3-g]quinolinium perchlorate |
Purity | ≥90% (coupling to thiols) |
IUPAC Name | 4-[9-(dimethylamino)-11,11-dimethyl-3,4-dihydro-2H-naphtho[2,3-g]quinolin-1-ium-1-yl]-N-[2-(2,5-dioxopyrrol-1-yl)ethyl]butanamide;perchlorate |
Canonical SMILES | CC1(C2=CC3=[N+](CCCC3=CC2=CC4=C1C=C(C=C4)N(C)C)CCCC(=O)NCCN5C(=O)C=CC5=O)C.[O-]Cl(=O)(=O)=O |
InChI | InChI=1S/C31H36N4O3.ClHO4/c1-31(2)25-19-24(33(3)4)10-9-21(25)17-23-18-22-7-5-14-34(27(22)20-26(23)31)15-6-8-28(36)32-13-16-35-29(37)11-12-30(35)38;2-1(3,4)5/h9-12,17-20H,5-8,13-16H2,1-4H3;(H,2,3,4,5) |
InChI Key | NIZBDUMEZAIMFT-UHFFFAOYSA-N |
MDL Number | MFCD04040681 |
NACRES | NA.32 |
Product Specification |
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Excitation | 610 |
Emission | 637 |
Properties Quality Level | 100 |
Storage | −20 °C |
Application | ATTO 610 belongs to a new generation of fluorescent labels invented by ATTO-TEC. The dye is designed for application in the area of life science, e.g. labeling of DNA, RNA or proteins. Characteristic features of the label are strong absorption, high fluorescence quantum yield, high photostability, good water solubility, and very little triplet formation. ATTO 610 is a pH sensitive product. While practically stable up to pH 8.5, it slowly degrades at higher pH. Maleimides are well suited for coupling to thiol groups. This is similar to iodacetamides, but maleimides do react more thiol selective. They do not show significant reaction with histidine or methionine. Hydrolysis of maleimides to a mixture of isomeric nonreactive maleamic acids can compete significantly with thiol modification, particularly above pH 8. Maleimides may be used for labeling of amines, which usually requires a higher pH than reaction of maleimides with thiols. |
Computed Properties | |
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Hydrogen Bond Donor Count | 1 |
Hydrogen Bond Acceptor Count | 8 |
Rotatable Bond Count | 8 |
Exact Mass | 612.2350772 g/mol |
Monoisotopic Mass | 612.2350772 g/mol |
Topological Polar Surface Area | 147Ų |
Heavy Atom Count | 43 |
Formal Charge | 0 |
Complexity | 1250 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 2 |
Compound Is Canonicalized | Yes |
Applications of Fluorescent Probes & Dyes
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