ATTO 610 maleimide

What We Offer

ATTO 610 maleimide

ATTO 610 maleimide

Catelog Number F10-0131
Category ATTO
Molecular Formula C31H37ClN4O7
Molecular Weight 613.10
Catalog Number Size Price Quantity
F10-0131 -- $--

Chemical Information

Synonyms ATTO 610-4; atto610-maleimide; Atto 610 maleimide, BioReagent, suitable for fluorescence, >=90% (coupling to thiols); 4-[9-(dimethylamino)-11,11-dimethyl-3,4-dihydro-2H-naphtho[2,3-g]quinolin-1-ium-1-yl]-N-[2-(2,5-dioxopyrrol-1-yl)ethyl]butanamide;perchlorate; 9-(dimethylamino)-1-(4-{[2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl]amino}-4-oxobutyl)-11,11-dimethyl-2,3,4,11-tetrahydronaphtho[2,3-g]quinolinium perchlorate
Purity ≥90% (coupling to thiols)
IUPAC Name 4-[9-(dimethylamino)-11,11-dimethyl-3,4-dihydro-2H-naphtho[2,3-g]quinolin-1-ium-1-yl]-N-[2-(2,5-dioxopyrrol-1-yl)ethyl]butanamide;perchlorate
Canonical SMILES CC1(C2=CC3=[N+](CCCC3=CC2=CC4=C1C=C(C=C4)N(C)C)CCCC(=O)NCCN5C(=O)C=CC5=O)C.[O-]Cl(=O)(=O)=O
InChI InChI=1S/C31H36N4O3.ClHO4/c1-31(2)25-19-24(33(3)4)10-9-21(25)17-23-18-22-7-5-14-34(27(22)20-26(23)31)15-6-8-28(36)32-13-16-35-29(37)11-12-30(35)38;2-1(3,4)5/h9-12,17-20H,5-8,13-16H2,1-4H3;(H,2,3,4,5)
InChI Key NIZBDUMEZAIMFT-UHFFFAOYSA-N
MDL Number MFCD04040681
NACRES NA.32

Product Specification

Excitation 610
Emission 637
Properties Quality Level 100
Storage −20 °C
Application ATTO 610 belongs to a new generation of fluorescent labels invented by ATTO-TEC. The dye is designed for application in the area of life science, e.g. labeling of DNA, RNA or proteins. Characteristic features of the label are strong absorption, high fluorescence quantum yield, high photostability, good water solubility, and very little triplet formation. ATTO 610 is a pH sensitive product. While practically stable up to pH 8.5, it slowly degrades at higher pH. Maleimides are well suited for coupling to thiol groups. This is similar to iodacetamides, but maleimides do react more thiol selective. They do not show significant reaction with histidine or methionine. Hydrolysis of maleimides to a mixture of isomeric nonreactive maleamic acids can compete significantly with thiol modification, particularly above pH 8. Maleimides may be used for labeling of amines, which usually requires a higher pH than reaction of maleimides with thiols.

Computed Properties

Hydrogen Bond Donor Count 1
Hydrogen Bond Acceptor Count 8
Rotatable Bond Count 8
Exact Mass 612.2350772 g/mol
Monoisotopic Mass 612.2350772 g/mol
Topological Polar Surface Area 147Ų
Heavy Atom Count 43
Formal Charge 0
Complexity 1250
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 2
Compound Is Canonicalized Yes
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