Anti-Mouse IgG (whole molecule)−ATTO 488 antibody produced in goat

Product Introduction

IgG is the most abundant antibody in human serum. It is secreted by B cells andis found in blood. It consists of four polypeptide chains, made of two identical 50 kDa γ heavy (H) chains and two identical 25 kDa κ or λ light (L) chains, that is linked together by inter-chain disulfide bonds. IgG contains four isotypes IgG1, IgG2, IgG3 and IgG4.Immunoglobulin G (IgG) is a glycoprotein antibody that regulates immune responses such as phagocytosis and is also involved in the development of autoimmune diseases. Anti-Mouse IgG (whole molecule)-ATTO 488 antibody is specific for mouse IgG. The product is purified from goat anti-mouse IgG antiserum to remove all goat serum proteins, including immunoglobulins that do not specifically bind to mouse IgG. The antibody preparation is solid phase adsorbed with human serum proteins to ensure minimal cross reactivity.

Chemical Information
NACRES	NA.46

Product Specification
Properties Concentration	~2 mg/mL, affinity isolated antibody, buffered aqueous solution
Application	Anti-Mouse IgG (whole molecule)?ATTO 488 antibody produced in goat has been used: in immunofluorescence confocal microscopic assay for p65 localization in immunohistochemical analysisApplications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.Immunofluorescence (1 paper)