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Anti-Human IgG (whole molecule)−ATTO 488 antibody produced in goat
| Catalog Number | F10-0148 |
| Category | ATTO Dyes |
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
Human IgGs are glycoprotein antibodies that contain two equivalent light chains and a pair of identical heavy chains. IgGs have four distinct isoforms, ranging from IgG1 to IgG4. These antibodies regulate immunological responses to allergy and pathogenic infections. IgGs have also been implicated in complement fixation and autoimmune disorders,. ATTO 488-goat anti-human IgGs are known to associate with human IgGs.
Chemical Information
Product Specification
Application
| NACRES | NA.46 |
| Properties Concentration | ~1 mg/mL |
Anti-Human IgG (whole molecule)-ATTO 488 antibody: a fluorescently labeled antibody produced by goats, with high specificity, finding applications in various research and diagnostic settings.
Flow Cytometry: A pivotal application of this antibody in flow cytometry involves its crucial role in identifying and quantifying human IgG in diverse samples. The ATTO 488 dye, with its fluorescence properties, enables clear and precise detection of bound antibodies, aiding researchers in scrutinizing immune cell populations and analyzing antibody responses under varying conditions.
Immunofluorescence Microscopy: Within the domain of immunofluorescence microscopy, the Anti-Human IgG (whole molecule)-ATTO 488 antibody emerges as a standout tool, facilitating the visualization of human IgG distribution within cells or tissue sections. The fluorescent label, known for its sensitivity and specificity, allows for detailed imaging of antigen-antibody interactions, essential for exploring cellular localization and protein expression patterns.
Western Blotting: Another notable application of this antibody is its role in Western blotting, where it excels in detecting human IgG within protein samples separated via gel electrophoresis. The ATTO 488 fluorescence aids in visualizing protein bands post-transfer to a membrane, providing researchers with a means to confirm the presence and study the characteristics of IgG antibodies in various biological samples.
Diagnostics: In diagnostic assays, the Anti-Human IgG (whole molecule)-ATTO 488 antibody emerges as a valuable ally for detecting human IgG antibodies in patient samples. Its exceptional specificity and fluorescent labeling ensure precise identification of immunoglobulins in assays like ELISA, playing a crucial role in diagnosing autoimmune diseases and monitoring immune responses.
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