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N-(3-Triethylammoniumpropyl)-4-(4-(dibutylamino)styryl)pyridinium dibromide | CAS 149838-22-2
| Catalog Number | A16-0079 |
| Category | Nerve Terminal Probes |
| Molecular Formula | C30H49Br2N3 |
| Molecular Weight | 611.55 |
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
A membrane-permeant fluorescent probe that is useful in cell biology and neurobiology for investigation of synaptic activity at synapses and at neuromuscular junctions. This probe is non-fluorescent until it binds to membrane.
Chemical Information
Product Specification
Application
| Synonyms | NeurotransGreen C4; MM1-43; 3-[4-[(E)-2-[4-(dibutylamino)phenyl]ethenyl]pyridin-1-ium-1-yl]propyl-triethylazanium dibromide |
| Canonical SMILES | CCCCN(CCCC)C1=CC=C(C=C1)C=CC2=CC=[N+](C=C2)CCC[N+](CC)(CC)CC.[Br-].[Br-] |
| InChI | InChI=1S/C30H49N3.2BrH/c1-6-11-23-32(24-12-7-2)30-18-16-28(17-19-30)14-15-29-20-25-31(26-21-29)22-13-27-33(8-3,9-4)10-5;;/h14-21,25-26H,6-13,22-24,27H2,1-5H3;2*1H/q+2;;/p-2 |
| InChIKey | VZUVCAGXYLMFEC-UHFFFAOYSA-L |
| Excitation | 541 |
| Emission | 567 |
N-(3-Triethylammoniumpropyl)-4-(4-(dibutylamino)styryl)pyridinium dibromide is a fluorescent dye with versatile applications in biological and chemical research. Here are some key applications of this compound:
Cell Imaging: This fluorescent dye is used extensively in live cell imaging to visualize cellular structures and processes. By tagging cellular components such as proteins or membranes, researchers can observe real-time cellular dynamics under a microscope. This provides valuable insights into cellular functions, interactions, and morphological changes.
Flow Cytometry: The fluorescent properties of this compound make it suitable for use in flow cytometry, a technique used to analyze the physical and chemical characteristics of cells or particles. When conjugated to antibodies or other ligands, it allows for the identification and quantification of specific cell populations. This is crucial in immunology, cancer research, and various diagnostic applications.
Molecular Probes: N-(3-Triethylammoniumpropyl)-4-(4-(dibutylamino)styryl)pyridinium dibromide acts as a molecular probe for studying nucleic acid interactions. It can intercalate with DNA or RNA, making it useful for fluorescence-based assays that monitor nucleic acid hybridization, melting, or other conformational changes. This helps in advancing our understanding of genetic materials and their functions.
Fluorescent Sensors: This compound can be employed in the development of fluorescent sensors for detecting various analytes, such as ions, small molecules, or environmental contaminants. By designing sensors that change their fluorescence properties in response to specific targets, researchers can create sensitive and specific detection methods. These sensors have applications in environmental monitoring, medical diagnostics, and chemical analysis.
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