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Flutax 2 | 301844-13-3
| Catalog Number | A16-0006 |
| Category | Nerve Terminal Probes |
| Molecular Formula | C71H64F2N2O21 |
| Molecular Weight | 1319.28 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| A16-0006 | -- | $-- |
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Product Introduction
Flutax 2 is a green fluorescent taxol derivative used for imaging microtubule.
Chemical Information |
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| Synonyms | (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-9-[(2R,3S)-3-(benzoylamino)-2-hydroxy-1-oxo-3-phenylpropoxy]-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-4-yl ester N-[(2',7'-difluoro-3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)carbonyl]-L-alanine |
| Purity | ≥90% by HPLC |
| Canonical SMILES | CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)OC(=O)C(C)NC(=O)C8=CC(=C(C=C8)C9=C1C=C(C(=O)C=C1OC1=CC(=C(C=C19)F)O)F)C(=O)O)C)OC(=O)C |
| InChI | InChI=1S/C71H64F2N2O21/c1-33-51(93-67(88)57(80)56(37-17-11-8-12-18-37)75-62(82)38-19-13-9-14-20-38)31-71(89)61(95-66(87)39-21-15-10-16-22-39)59-69(7,60(81)58(91-35(3)76)55(33)68(71,5)6)52(30-53-70(59,32-90-53)96-36(4)77)94-65(86)34(2)74-63(83)40-23-24-41(42(25-40)64(84)85)54-43-26-45(72)47(78)28-49(43)92-50-29-48(79)46(73)27-44(50)54/h8-29,34,51-53,56-59,61,78,80,89H,30-32H2,1-7H3,(H,74,83)(H,75,82)(H,84,85)/t34-,51-,52-,53+,56-,57+,58+,59-,61-,69+,70-,71+/m0/s1 |
| InChI Key | UTOYCOKRJWZPNT-SQNCZLKBSA-N |
- Product Specification
- Application
| Storage | Store at -20°C |
Flutax 2, a fluorescent taxol derivative renowned in bioscience research, is prized for its versatility in unraveling the intricacies of microtubule dynamics and various cellular processes. Here are four key applications of Flutax 2:
Microtubule Dynamics Studies: With its specific binding affinity for microtubules, Flutax 2 grants researchers the ability to peer into the dynamic world of live cells. By harnessing the fluorescence emitted by Flutax 2, scientists delve into the growth and shrinkage patterns of microtubules, shedding light on critical processes like cell division, intracellular transport, and cytoskeletal architecture.
Cancer Research: At the forefront of oncological inquiry, Flutax 2 plays a pivotal role in investigating the impact of anti-cancer drugs targeting microtubules, such as taxanes. Through meticulous observation of Flutax 2-labeled microtubules under drug-induced stress, researchers glean valuable insights into the mechanisms of action and resistance mechanisms. This knowledge fuels the advancement of more potent chemotherapy regimens.
High-Content Screening: Embraced by automated imaging platforms for comprehensive screening endeavors, Flutax 2 emerges as a beacon for identifying compounds that influence microtubule stability and functionality. Its fluorescent signature renders Flutax 2 an optimal marker for large-scale screening assays, facilitating the discovery of novel drug candidates with promising therapeutic applications.
Neuroscience Research: In the realm of neuroscience exploration, Flutax 2 emerges as a key ally in unraveling the enigmatic role of microtubules in neuronal dynamics and development. By tagging microtubules in neurons with precision, researchers embark on a journey to decipher the intricate dynamics and organization within the neural landscape. This endeavor is paramount for delving into neurodegenerative disorders and forging innovative neuroprotective strategies.
Applications of Fluorescent Probes & Dyes
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