MitoMark Red I | 167095-09-2
Catalog Number | A16-0007 |
Category | Mitochondrial Fluorescent Probes |
Molecular Formula | C32H32Cl2N2O |
Molecular Weight | 531.52 |
Catalog Number | Size | Price | Quantity |
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A16-0007 | -- | $-- |
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Product Introduction
MitoMark Red I is a red fluorescent mitochondrial stain.
Chemical Information |
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Synonyms | 9-[4-(Chloromethyl)phenyl]-2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-xantheno[2,3,4-ij:5,6,7-i'j']diquinolizin-18-ium chloride; MitoTracker Red; MTRed; CMXRos; Chloromethyl-X-rosamine |
Purity | ≥90% by HPLC |
IUPAC Name | 16-[4-(chloromethyl)phenyl]-3-oxa-23-aza-9-azoniaheptacyclo[17.7.1.15,9.02,17.04,15.023,27.013,28]octacosa-1(27),2(17),4,9(28),13,15,18-heptaene;chloride |
Canonical SMILES | C1CC2=C3C(=C4C(=C2)C(=C5C=C6CCC[N+]7=C6C(=C5O4)CCC7)C8=CC=C(C=C8)CCl)CCCN3C1.[Cl-] |
InChI | InChI=1S/C32H32ClN2O.ClH/c33-19-20-9-11-21(12-10-20)28-26-17-22-5-1-13-34-15-3-7-24(29(22)34)31(26)36-32-25-8-4-16-35-14-2-6-23(30(25)35)18-27(28)32;/h9-12,17-18H,1-8,13-16,19H2;1H/q+1;/p-1 |
InChI Key | IKEOZQLIVHGQLJ-UHFFFAOYSA-M |
- Product Specification
- Application
Storage | Store at -20°C |
MitoMark Red I, a specialized fluorescent dye tailored for mitochondria labeling in live cell imaging, finds diverse applications in scientific research. Here are four key applications of MitoMark Red I:
Live Cell Imaging: In the realm of live cell imaging, MitoMark Red I emerges as a crucial tool for tracking and studying mitochondria dynamics in real-time. By facilitating the visualization of processes like fission, fusion, and cellular movement, researchers gain valuable insights into the intricate functioning and health of mitochondria across various cellular contexts and pathological states.
Apoptosis Studies: Delving into apoptosis exploration, MitoMark Red I shines as it aids in the detection of alterations in mitochondrial membrane potential—a hallmark of programmed cell death. Through the staining of mitochondria, researchers can closely monitor the early events of apoptosis, unraveling the underlying mechanisms of cell demise. This knowledge is pivotal for unraveling the intricate roles of mitochondria in diseases like cancer and neurodegeneration.
Drug Screening: Transitioning to drug screening endeavors, MitoMark Red I plays a pivotal role in high-throughput assays designed to assess the impacts of pharmaceutical compounds on mitochondrial function. By scrutinizing changes in mitochondrial morphology and functionality post-drug exposure, researchers can pinpoint potential mitochondrial toxicants or therapeutic agents with precision. This facilitates the advancement and safety assessment of novel drug candidates.
Metabolic Studies: Lastly, in the domain of metabolic research, MitoMark Red I takes center stage for its contribution to unraveling mitochondrial bioenergetics. By enabling the measurement of key parameters, such as mitochondrial respiration and ATP production under diverse experimental conditions, this dye empowers scientists to deepen their understanding of metabolic processes. Such insights are instrumental in tackling energy metabolism disorders and formulating effective therapeutic strategies for metabolic ailments.
Computed Properties | |
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Hydrogen Bond Donor Count | 0 |
Hydrogen Bond Acceptor Count | 3 |
Rotatable Bond Count | 2 |
Exact Mass | 530.1891690 g/mol |
Monoisotopic Mass | 530.1891690 g/mol |
Topological Polar Surface Area | 15.5Ų |
Heavy Atom Count | 37 |
Formal Charge | 0 |
Complexity | 995 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 2 |
Compound Is Canonicalized | Yes |
Patents
Publication Number | Title | Priority Date |
---|---|---|
KR-102480069-B1 | Composition for diagnosing diabetic retinopathy using biomarkers, method for providing information for diagnosing diabetic retinopathy, and screening method for substances for treatment of diabetic retinopathy | 2022-09-08 |
CN-115141801-A | Methods, kits and uses for the analysis of different lymphocyte subsets based on mitochondrial metabolic activity | 2022-08-16 |
CN-115232820-A | Application of miR-142-3p in the treatment of high salt-induced cardiac fibrosis | 2022-05-23 |
CN-114716635-A | A kind of multifunctional polyurea acid derivative and its preparation method and application | 2022-05-12 |
CN-114854816-A | A keratinocyte exosome-mediated approach to promote hair growth | 2022-05-09 |
Applications of Fluorescent Probes & Dyes
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