Inquiry Basket
Mca-PLA-Nva-Dap(Dnp)-AR-NH2
| Catalog Number | A18-0036 |
| Category | Fluorescent Enzyme Substrates |
| Molecular Formula | C49H68N14O15 |
| Molecular Weight | 1093.1 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| A18-0036 | -- | $-- |
- Worldwide Delivery
- Quality Assurance
- 24/7 Customer Service
Product Introduction
Mca-PLA-Nva-Dap(Dnp)-AR-NH2 is a fluorogenic substrate for matrix metalloproteinase-2 (MMP-2). It is cleaved by MMP-2 to release the fluorescent moiety 7-methoxycoumarin-4-acetyl (Mca), which can be used to quantify MMP-2 activity.
Chemical Information |
|
|---|---|
| Synonyms | Matrix Metalloproteinase-2 Fluorogenic Substrate; MMP-2 Fluorogenic Substrate; 1-[(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-prolyl-L-leucyl-L-alanyl-L-norvalyl-3-[(2,4-dinitrophenyl)amino]-L-alanyl-L-alanyl-L-argininamide |
| Purity | ≥95% |
| IUPAC Name | (2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(2,4-dinitroanilino)-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-1-[2-(7-methoxy-2-oxochromen-4-yl)acetyl]pyrrolidine-2-carboxamide |
| Canonical SMILES | CCCC(C(=O)NC(CNC1=C(C=C(C=C1)[N+](=O)[O-])[N+](=O)[O-])C(=O)NC(C)C(=O)NC(CCCN=C(N)N)C(=O)N)NC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C2CCCN2C(=O)CC3=CC(=O)OC4=C3C=CC(=C4)OC |
| InChI | InChI=1S/C49H68N14O15/c1-7-10-34(45(69)60-36(24-54-32-16-13-29(62(73)74)22-38(32)63(75)76)47(71)56-26(4)43(67)57-33(42(50)66)11-8-17-53-49(51)52)58-44(68)27(5)55-46(70)35(19-25(2)3)59-48(72)37-12-9-18-61(37)40(64)20-28-21-41(65)78-39-23-30(77-6)14-15-31(28)39/h13-16,21-23,25-27,33-37,54H,7-12,17-20,24H2,1-6H3,(H2,50,66)(H,55,70)(H,56,71)(H,57,67)(H,58,68)(H,59,72)(H,60,69)(H4,51,52,53)/t26-,27-,33-,34-,35-,36-,37-/m0/s1 |
| InChI Key | YFZQNMDPUINDHE-QEFIOWGDSA-N |
- Product Specification
| Storage | Store at -20°C |
Computed Properties | |
|---|---|
| XLogP3 | 1.3 |
| Hydrogen Bond Donor Count | 10 |
| Hydrogen Bond Acceptor Count | 17 |
| Rotatable Bond Count | 27 |
| Exact Mass | 1092.49885752 g/mol |
| Monoisotopic Mass | 1092.49885752 g/mol |
| Topological Polar Surface Area | 442Ų |
| Heavy Atom Count | 78 |
| Formal Charge | 0 |
| Complexity | 2250 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 7 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
Applications of Fluorescent Probes & Dyes
Get More Product Details?
