Calcein Blue | 54375-47-2

Calcein Blue, a highly fluorescent dye with exceptional staining properties, finds widespread use in diverse scientific fields. Here are four key applications of Calcein Blue:

Cell Viability Assays: In the realm of cell biology, Calcein Blue takes center stage for its pivotal role in assessing cell health and viability. When cells are teeming with life and metabolic activity, Calcein Blue permeates their membranes and emits a fluorescent glow, furnishing a direct gauge of cellular viability. This application holds immense significance in drug screening endeavors, cytotoxicity investigations, and evaluating the impacts of diverse treatments on cell populations.

Calcium Imaging: In the intricate domains of neurobiology and cell signaling, Calcein Blue emerges as a stalwart for calcium imaging applications, facilitating the monitoring of intracellular calcium dynamics. By infusing cells with Calcein Blue, researchers embark on a journey to unveil the mysteries of calcium flux through the lens of fluorescence microscopy. This method is paramount in dissecting cellular phenomena such as muscle contraction, neurotransmitter release, and the labyrinthine pathways of signal transduction.

Bone Labeling: Delving into the realms of histology, Calcein Blue steps into the spotlight as a trusted bone marker, aiding researchers in the visualization and labeling of mineralizing tissues. Administered to animal subjects, Calcein Blue binds to regions where nascent bone formation is underway, enabling the observation of bone growth and remodeling processes.