BODIPY TR Cadaverine | CAS 217190-24-4

Catalog Number	F01-0178
Category	BODIPY
Molecular Formula	C26H28BClF2N4O2S
Molecular Weight	544.86

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Product Introduction

BODIPY TR Cadaverine is an aliphatic-amine analog of the red-fluorescent dye, of which the primary amine can be coupled to aldehydes and ketones to yield a reversible Schiff Base product that can be transformed to a stable amine derivative using a reducing agent like sodium borohydride or sodium cyanoborohydride.

Chemical Information
Product Specification
Application

Synonyms	EverFluor TR Cadaverine; 5-(((4-(4,4-Difluoro-5-(2-Thienyl)-4-Bora-3a,4a-Diaza-s-Indacene-3-yl)phenoxy)acetyl)amino)pentylamine Hydrochloride
Appearance	Solid Powder

Excitation	492
Emission	492

BODIPY TR Cadaverine is a fluorescent dye featuring the BODIPY (boron-dipyrromethene) core structure, which emits in the red region of the spectrum. This dye is commonly used for labeling biomolecules, thanks to its bright fluorescence and excellent photostability. The inclusion of the cadaverine group enables the dye to specifically conjugate with amine-containing compounds, such as proteins, peptides, and other biomolecules, which makes it an effective tool for a range of biological and chemical applications.

One of the primary applications of BODIPY TR Cadaverine is in fluorescence imaging for live-cell studies. Its red fluorescence minimizes interference from cellular autofluorescence, making it ideal for imaging in complex biological samples. The dye is used to track and study cellular processes like protein localization, trafficking, and receptor binding in real time, providing valuable insight into cellular behavior and dynamics.

Another key application of BODIPY TR Cadaverine is in tissue imaging. Due to its strong fluorescence and stability, it is widely used for the labeling and tracking of biomolecules in tissue sections. This application is particularly important in cancer research and other disease models, where researchers use the dye to monitor the distribution and behavior of specific proteins or biomolecular interactions within tissues, aiding in the study of disease progression and therapeutic responses.

BODIPY TR Cadaverine is also used in the development of molecular sensors and probes. Its ability to bind specifically to amine-containing molecules makes it ideal for creating biosensors that detect target molecules or changes in the biological environment. This application has widespread use in biochemical assays, including enzyme activity detection, and in monitoring the presence of specific metabolites in complex samples.

Additionally, BODIPY TR Cadaverine is employed in antibody and protein labeling for immunoassays, flow cytometry, and immunohistochemistry. The dye's ability to attach to amine groups allows it to be conjugated with antibodies or other proteins, enabling the detection of specific biomarkers or targets in biological samples. This application is crucial in diagnostics and molecular research, where understanding protein interactions and cellular markers is essential.