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BODIPY
BODIPY FL C5-Sphingomyelin

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BODIPY FL C5-Sphingomyelin

Catalog Number	F01-0195
Category	BODIPY
Molecular Formula	C39H66BF2N4O6P
Molecular Weight	766.54

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Product Introduction

BODIPY FL C5-Sphingomyelin is a green-fluorescent derivative of sphingomyelin, a sphingolipid in animal cell membranes and the myelin sheath that surrounds some nerve cell axons. This compound has been used in sphingolipid metabolism and transport research. It is non-ionic and relatively insensitive to environment and pH changes.

Chemical Information
Application

Synonyms	EverFluor FL C5-Sphingomyelin; N-(4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Pentanoyl)Sphingosyl Phosphocholine
Appearance	Solid Powder

BODIPY FL C5-Sphingomyelin, a fluorescent lipid analog, plays a pivotal role in diverse biological research endeavors, particularly concerning membrane dynamics and lipid trafficking. Here are four key applications of BODIPY FL C5-Sphingomyelin:

Membrane Dynamics Studies: Delving into the intricacies of cell membranes, researchers leverage BODIPY FL C5-Sphingomyelin to unravel the dynamics of lipid rafts and membrane fluidity. By incorporating this fluorescent probe into cell membranes, scientists embark on a journey of visualizing and tracking lipid movement in real-time using fluorescence microscopy. This approach deepens our comprehension of how lipid organization shapes cellular processes and membrane-related functionalities.

Lipid Trafficking Analysis: The exploration of sphingolipid movement within cells finds its ally in BODIPY FL C5-Sphingomyelin. This versatile probe empowers researchers to monitor the journey of sphingomyelin from the Golgi apparatus to the plasma membrane and other cellular organelles. Through the analysis of lipid trafficking, valuable insights emerge regarding cell signaling, membrane biogenesis, and lipid-linked pathological conditions.

Live Cell Imaging: Operating at the frontier of live-cell imaging applications, BODIPY FL C5-Sphingomyelin facilitates the examination of lipid behavior under physiological conditions. The fluorescent properties of this analog enable the visualization of dynamic lipid interactions and cellular transformations within living cells without disrupting normal cellular function. This methodology aids in dissecting real-time lipid dynamics in response to various stimuli or therapeutic interventions.

Drug Interaction Studies: In the realm of drug interaction investigations, BODIPY FL C5-Sphingomyelin emerges as a crucial tool for deciphering the impact of pharmaceutical compounds on lipid membranes. By observing alterations in sphingomyelin behavior following drug administration, researchers gain insights into the effects of drugs on membrane integrity and lipid-mediated signaling pathways. This knowledge is instrumental in elucidating drug mechanisms and identifying potential lipid metabolism-related side effects.