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BODIPY 558/568 C12 | CAS 158757-84-7
| Catalog Number | F01-0161 |
| Category | BODIPY |
| Molecular Formula | C25H31BF2N2O2S |
| Molecular Weight | 472.4 |
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
This long-chain fluorescent lipid probe is used to visualize membrane dynamics. Buy fluorescent dyes online for lipid transport and trafficking studies.
Chemical Information
Application
Computed Properties
| Synonyms | 4,4-Difluoro-5-(2-Thienyl)-4-Bora-3a,4a-Diaza-s-Indacene-3-Dodecanoic Acid |
| IUPAC Name | 12-(2,2-difluoro-12-thiophen-2-yl-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-1(12),4,6,8,10-pentaen-4-yl)dodecanoate;hydron |
| Canonical SMILES | [H+].[B-]1(N2C(=CC=C2CCCCCCCCCCCC(=O)[O-])C=C3[N+]1=C(C=C3)C4=CC=CS4)(F)F |
| InChI | InChI=1S/C25H31BF2N2O2S/c27-26(28)29-20(11-8-6-4-2-1-3-5-7-9-13-25(31)32)14-15-21(29)19-22-16-17-23(30(22)26)24-12-10-18-33-24/h10,12,14-19H,1-9,11,13H2,(H,31,32) |
| InChIKey | PHUIDILRCYWCMI-UHFFFAOYSA-N |
| Appearance | Solid Powder |
BODIPY 558/568 C12, a versatile fluorescent lipid probe, is widely utilized in biological and biochemical research for lipid imaging and tracking. Here are four key applications of BODIPY 558/568 C12:
Lipid Trafficking Studies: Delving into the intricate dynamics of lipid movements within cells, researchers employ BODIPY 558/568 C12 to gain insights into the transport pathways of lipids. By integrating this fluorescent probe into lipid molecules, scientists reveal the hidden journey of lipids within cells, shedding light on lipid metabolism, distribution, and their crucial role in processes like membrane formation and signaling.
Membrane Dynamics: At the forefront of cell biology, BODIPY 558/568 C12 serves as a vital tool for exploring the behavior and composition of cellular membranes. Its fluorescence properties enable researchers to track changes in membrane structure, fluidity, and organization in response to various stimuli or treatments. This valuable information plays a pivotal role in unraveling the functions associated with membranes and understanding disorders stemming from membrane abnormalities.
Live Cell Imaging: Renowned for its exceptional photostability and vibrant fluorescence, BODIPY 558/568 C12 finds its niche in live cell imaging applications. Scientists leverage its capabilities to examine the spatial and temporal distribution of lipids within living cells seamlessly without disrupting cellular activities. This real-time imaging prowess supports investigations into lipid-related signal transduction and cellular transformations, offering critical insights into dynamic cellular processes.
Lipid Metabolism Research: A cornerstone in metabolic studies, BODIPY 558/568 C12 is instrumental in tracing lipid incorporation and modifications across various biological systems. By labeling with BODIPY 558/568 C12, researchers track the uptake and assimilation of fatty acids in cells, unraveling metabolic pathways and energy equilibrium.
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 12 |
| Exact Mass | 472.2167359 g/mol |
| Monoisotopic Mass | 472.2167359 g/mol |
| Topological Polar Surface Area | 76.3Ų |
| Heavy Atom Count | 33 |
| Formal Charge | 0 |
| Complexity | 796 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 2 |
| Compound Is Canonicalized | Yes |
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