BDP TMR NHS ester

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BDP TMR NHS ester

BDP TMR NHS ester | 485397-12-4

Catelog Number R01-0011
Category BODIPY
Molecular Formula C25H24BF2N3O5
Molecular Weight 495.28
Catalog Number Size Price Quantity
R01-0011 -- $--

Product Introduction

BDP TMR is a borondipyrromethene dye, analog of BODIPY® TMR. This is an amine-reactive NHS ester for the labeling of proteins, peptides, and other molecules with amino groups.BDP TMR is a dye for TAMRA channel, which is however much brighter than TAMRA. Because of rather long life time of excited state, this fluorophore is a good choice for fluorescence anisotropy measurements, especially with the short linker offered. Fluorescence polarization is an excellent method for high throughput binding assays.

Chemical Information

Synonyms BODIPY TMR NHS Ester; (2,5-dioxopyrrolidin-1-yl) 3-[2,2-difluoro-12-(4-methoxyphenyl)-4,6-dimethyl-1-aza-3-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-3,5,7,9,11-pentaen-5-yl]propanoate
Purity NMR 1H, HPLC-MS (95%)
IUPAC Name (2,5-dioxopyrrolidin-1-yl) 3-[2,2-difluoro-12-(4-methoxyphenyl)-4,6-dimethyl-1-aza-3-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-3,5,7,9,11-pentaen-5-yl]propanoate
Canonical SMILES [B-]1(N2C(=CC=C2C3=CC=C(C=C3)OC)C=C4[N+]1=C(C(=C4C)CCC(=O)ON5C(=O)CCC5=O)C)(F)F
InChI InChI=1S/C25H24BF2N3O5/c1-15-20(9-13-25(34)36-31-23(32)11-12-24(31)33)16(2)29-22(15)14-18-6-10-21(30(18)26(29,27)28)17-4-7-19(35-3)8-5-17/h4-8,10,14H,9,11-13H2,1-3H3
InChI Key XMAZILQWJQABLQ-UHFFFAOYSA-N
Solubility good in most organic solvents (DMF, DMSO, DCM, acetone, etc.)
Appearance purple solid

Product Specification

Fluorescence Quantum Yield 0.95
Excitation 545
Emission 570

Computed Properties

Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 8
Rotatable Bond Count 7
Exact Mass 495.1777074 g/mol
Monoisotopic Mass 495.1777074 g/mol
Topological Polar Surface Area 80.8Ų
Heavy Atom Count 36
Formal Charge 0
Complexity 1060
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes
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