BDY 650-X, SE

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BDY 650-X, SE

BDY 650-X, SE | CAS 235439-04-0

Catalog Number R01-0008
Category BODIPY
Molecular Formula C33H32BF2N5O6
Molecular Weight 643.44
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Product Introduction

BDY 650-X, SE is a reactive fluorescent probe that features a succinimidyl ester group, facilitating efficient amine-reactive conjugation in labeling applications. This compound is incorporated into bioconjugation protocols to enable the visualization and tracking of biomolecules, leveraging its compatibility with primary amines on proteins, peptides, and other amine-containing substrates. BDY 650-X, SE supports surface modification and polymer functionalization through its stable linkage formation, making it a reliable choice for fluorescence-based assays and imaging studies.

  • Chemical Information

  • Product Specification

  • Application

  • Computed Properties

  • Patents

Chemical Information

Synonyms BDP 650/665 X NHS ester;(T-4)-[2-[4-[2-[2-[([2,2'-Bi-1H-pyrrol]-5-yl-κN1)methylene]-2H-pyrrol-5-yl-κN]ethenyl]phenoxy]-N-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]acetamidato]difluoroboron
Purity ≥90%
IUPAC Name (2,5-dioxopyrrolidin-1-yl) 6-[[2-[4-[(E)-2-[2,2-difluoro-12-(1H-pyrrol-2-yl)-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-1(12),4,6,8,10-pentaen-4-yl]ethenyl]phenoxy]acetyl]amino]hexanoate
SMILES F[B-]1(F)[N+]2=C(C=CC2=CC3=CC=C(C4=CC=CN4)N13)/C=C/C5=CC=C(OCC(NCCCCCC(ON6C(CCC6=O)=O)=O)=O)C=C5
InChI InChI=1S/C33H32BF2N5O6/c35-34(36)39-24(11-12-25(39)21-26-13-16-29(40(26)34)28-5-4-20-37-28)10-7-23-8-14-27(15-9-23)46-22-30(42)38-19-3-1-2-6-33(45)47-41-31(43)17-18-32(41)44/h4-5,7-16,20-21,37H,1-3,6,17-19,22H2,(H,38,42)/b10-7+
InChIKey CDXXFTJLAKSQSR-JXMROGBWSA-N
Solubility Soluble to 64.34 mg/ml in DMSO.
Appearance Solid

Product Specification

ε, L⋅mol-1⋅cm-1 94000
Fluorescence Quantum Yield 0.52
Excitation 649
Emission 667

Application

Computed Properties

Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 9
Rotatable Bond Count 14
Exact Mass 643.2413702 g/mol
Monoisotopic Mass 643.2413702 g/mol
Topological Polar Surface Area 126Ų
Heavy Atom Count 47
Formal Charge 0
Complexity 1340
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 1
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

Patents

Publication Number Title Priority Date
WO-2020072491-A1 Brevican-binding peptides for brain tumor imaging 2018-10-01
US-2016121002-A1 Bioorthogonal Turn-on Probes 2013-05-06
US-2020188535-A1 Bioorthogonal Turn-on Probes 2013-05-06
US-2016022817-A1 Photoswitchable HDAC Inhibitors 2013-03-13
US-2019070295-A1 Photoswitchable HDAC Inhibitors 2013-03-13

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