2-(2-carboxyethyl)-5,5-difluoro-1,3,7,9-tetramethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide | 126250-37-1

2-(2-carboxyethyl)-5,5-difluoro-1,3,7,9-tetramethyl-5H-dipyrrolo[1,2-c:2’,1’-f][1,3,2]diazaborinin-4-ium-5-uide, more commonly referred to as a BODIPY dye, is a versatile fluorescent dye used in various scientific applications.

Fluorescence Imaging: This BODIPY dye is widely used in fluorescence imaging due to its high fluorescence quantum yield and photostability. These properties make it an excellent choice for tracking cellular processes in live-cell imaging studies. Researchers often employ it as a fluorescent probe in bioimaging for visualizing the distribution and interactions of biomolecules within cells.

Flow Cytometry: In flow cytometry, BODIPY dyes are utilized to label antibodies or other target-specific ligands for multiparametric analysis of cell populations. The dye’s bright fluorescence allows for clear detection and differentiation of cell subsets based on specific markers. This application is particularly useful in clinical diagnostics and immunological research where precise cell analysis is crucial.

Chemical Sensing: BODIPY dyes serve as excellent chemical sensors due to their sensitivity to changes in their environment, such as pH or ions. By incorporating them into chemical sensors, researchers can detect and quantify various analytes in complex samples. This capability is valuable in environmental monitoring, where detecting trace amounts of pollutants or biologically relevant molecules is essential.

Drug Discovery: In drug discovery, BODIPY dyes are used to label potential drug candidates or targets for high-throughput screening assays. Their intense fluorescence facilitates the identification of active compounds by enabling real-time monitoring of biochemical interactions. This application accelerates the drug development process by allowing rapid and efficient evaluation of compound libraries.